Invagination intestinale sur métastases multiples d’un mélanome malin

Darouichi, M.

doi:10.1016/j.jradio.2011.03.015

Cited by 6 publications

(4 citation statements)

References 10 publications

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“…Nevertheless, the prognosis of metastatic patients is still extremely poor, with a median survival time of about 7 months. [ 24 ] Patient 2 underwent complete surgical resection and lymph node dissection, 1 month after surgery, the patient died of systemic multi-organ circulatory failure. The prognosis of primary cases is slightly better than that of metastatic cases.…”

Section: Discussionmentioning

confidence: 99%

Duodenal malignant melanoma: Primary and metastatic case series and literature review

Zhou,

Li,

Liu

et al. 2024

Medicine

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Rationale: Duodenal malignant melanoma is rare, and its early clinical symptoms are insidious, making it difficult to diagnose in its early stages. Combined with previous literature, We explored the clinicopathological characteristics and v-raf murine sarcoma viral oncogene homolog B1 mutations in primary and metastatic duodenal malignant melanoma, in order to provide some experience on its differential diagnosis and treatment. Patient concerns: The 2 patients (a 63-year-old female [Patient 1] and a 54-year-old male [Patient 2]) experienced pain and discomfort in their upper abdomen. Additionally, one of them had a history of skin malignant melanoma. Diagnoses: Patient 1 was diagnosed with primary duodenal malignant melanoma; and Patient 2 was diagnosed with metastatic duodenal malignant melanoma. Interventions: Patient 1 underwent pancreaticoduodenectomy; and patient 2 underwent complete surgical resection and lymph node dissection. Outcomes: After surgery, Patient 1 survived after 26 months follow-up, and Patient 2 died of systemic multi-organ circulatory failure after 1 month follow-up. Lessons: Primary and metastatic cases should be diagnosed through previous medical history analysis and detailed physical and auxiliary examinations. This would enable a diagnosis based on characteristic histomorphology and immunohistochemical markers. An early diagnosis and surgical treatment can prolong patient survival and the molecular inspection of v-raf murine sarcoma viral oncogene homolog B1 mutations can guide follow-up treatment.

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Section: Discussionmentioning

confidence: 99%

Duodenal malignant melanoma: Primary and metastatic case series and literature review

Zhou,

Li,

Liu

et al. 2024

Medicine

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“…For patients with solitary duodenal metastasis or obvious intestinal obstructions, surgical resection can effectively relieve symptoms and prolong survival. Nevertheless, the prognosis of metastatic patients is still extremely poor, with a median survival time of about 7 months [24]. Patient 2 underwent complete surgical resection and lymph node dissection, 1 month after surgery, 5/9 the patient died of systemic multi-organ circulatory failure.…”

Section: Discussionmentioning

confidence: 99%

Duodenal Malignant Melanoma：Primary and Metastatic

zhou,

Li,

Liu

et al. 2023

Preprint

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Background Duodenal malignant melanoma is rare, and its early clinical symptoms are insidious, making it difficult to diagnose in its early stages. Methods We explored the clinicopathological characteristics of duodenal malignant melanomas and association with BRAF mutations. Hematoxylin and eosin staining, immunohistochemical marker detection, and BRAF V600E mutation inspection via Sanger sequencing for two clinical cases of duodenal malignant melanoma were performed. The relevant literature was reviewed, and the clinical pathology was analyzed. Results The two patients (a 63-year-old female [Patient 1] and a 54-year-old male [Patient 2]) experienced pain and discomfort in their upper abdomen; moreover, they had endoscopic space-occupying lesions in the second part of their duodenum and invasively growing solid sheets of round, oval, or polygonal microscopic atypical tumor. Additionally, one of them had skin malignant melanoma and pigmentation, whereas the other was positive for BRAF V600E mutation. Tumor cell immunohistochemical analysis detected Vim, HMB45, Melan-A, and S-100 positive expression. They both underwent surgical treatment; however, Patients 1 and 2 died after 1 and 28 months, respectively. Conclusion Primary and metastatic cases should be diagnosed through previous medical history analysis and detailed physical and auxiliary examinations. This would enable a diagnosis based on characteristic histomorphology and immunohistochemical markers. An early diagnosis and surgical treatment can prolong patient survival and the molecular inspection of BRAF mutations can guide follow-up treatment.

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“…Les sites majoritaires des lésions secondaires des mélanomes sont dans l'ordre, les poumons (18 à 38 %), les ganglions lymphatiques (5 à 34 %), le tube digestif (1 à 8 %), le foie (14 à 38 %) [1], le cerveau, les os et le coeur, avec comme lésion primitive une lésion cutanée du cuir chevelu, de la face, du cou, oculaire ou anale. Les mélanomes du cuir chevelu sont associés à une moins bonne survie que les autres lésions de la tête, du cou et du tronc.…”

Section: Discussionunclassified

“…Les métastases digestives des mélanomes sont assez fréquentes, L'intestin grêle est le site le plus touché (71 %) suivi par l'estomac (27 %) [1]. Il est cependant exceptionnel qu'elles soient révélatrices, tout particulièrement au niveau de l'estomac où elles sont rarement isolées et surviennent le plus souvent dans un contexte multi-métastatique.…”

Section: Introductionunclassified

Gastric metastasis revealing melanoma of the scalp. A case study and literature review

Benabdelhafid¹

2019

Batna J Med Sci

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Les métastases digestives des mélanomes sont assez fréquentes, L’intestin grêle est le site le plus touché suivi par l'estomac. Il est cependant exceptionnel qu’elles soient révélatrices, tout particulièrement au niveau de l'estomac où elles sont rarement isolées et surviennent le plus souvent dans un contexte multi-métastatique. Nous insistons à travers cette observation et sous la lumière d'une revue de la littérature sur les critères endoscopiques, les caractéristiques anatomo-pathologiques, et le profil évolutif afin d’améliorer la prise en charge et le pronostic de cette localisation qui reste péjorative.

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Invagination intestinale sur métastases multiples d’un mélanome malin

Cited by 6 publications

References 10 publications

Duodenal malignant melanoma: Primary and metastatic case series and literature review

Duodenal malignant melanoma: Primary and metastatic case series and literature review

Duodenal Malignant Melanoma：Primary and Metastatic

Gastric metastasis revealing melanoma of the scalp. A case study and literature review

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