Invasive aspergillosis with polyarthritis

Mekan, Sabeen; Saeed, Omar; Khan, Jibran

doi:10.1111/j.1439-0507.2004.01031.x

Cited by 17 publications

(2 citation statements)

References 13 publications

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“…Surprisingly, there were neither arguments for direct intra-inoculation nor haematogenous seeding in our observation where no source was found and no other infectious foci were identified despite extensive investigations. Of note, among the 16 cases of A. fumigatus arthritis reported, only two had no evidence of disseminated disease, similar to our patient [ 2 – 4 ].…”

Section: Discussionsupporting

confidence: 86%

Aspergillus arthritis and organ transplantation

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Cantarovich

Tattevin

et al. 2012

Clinical Kidney Journal

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We report a case of a kidney and pancreas transplanted patient, hospitalized for septic hip arthritis. The whole diagnostic work-up including synovial and bone biopsies remained negative. After inefficient empirical anti-bacterial antibiotic treatment, femoral head resection was performed and tissue analysis revealed Aspergillus fumigatus hyphae. Treatment with voriconazole along with hip replacement led to complete recovery. However, drug interaction between immunosuppressive and anti-fungal drugs was complicated by cellular acute graft rejection. Aspergillus fumigatus arthritis is an uncommon and serious infection that should be evoked especially in the case of resistance to anti-microbial antibiotics and/or an atypical clinical picture.

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Section: Discussionsupporting

confidence: 86%

Aspergillus arthritis and organ transplantation

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Cantarovich

Tattevin

et al. 2012

Clinical Kidney Journal

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“…The hip joint is most commonly involved joint followed by knee, wrist and ankle among the cases of articular aspergillosis [ 2 ]. Aspergillus genus includes more than 35 species of saprophytic moulds among which Aspergillus fumigatus is the most common pathogenic organism [ 10 ].…”

Section: Case Presentationmentioning

confidence: 99%

Disseminated Aspergillus flavus following septic arthritis in an immunocompetent patient: a case report

et al. 2014

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BackgroundAspergillosis is a rare cause of osteomyelitis and septic arthritis. Aspergillus osteomyelitis is a debilitating infection affecting both immunocompromised and immunocompetent patients. It is associated with a high incidence of morbidity and mortality. Infection with Aspergillus flavus species in the knee has been very rarely seen in the past.Case presentationWe present a case of septic arthritis of the knee in an Indian patient secondary to infection with Aspergillus flavus, which was earlier managed as a case of tuberculosis based on the endemicity of the condition, later leading to disseminated aspergillosis. There was no clinical feature or investigation suggesting immunocompromised state. Following knee arthrotomy, Aspergillus flavus was isolated and patient was subsequently managed with antifungals leading to recovery after three months.ConclusionsDisseminated aspergillosis can mimic tuberculosis both clinically and radiologically. Though fungal infections affect joints rarely but they must always be ruled out to avoid later complications.

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Fungal infections of bone and joint

Kemper¹,

Deresinski²

2009

Clinical Mycology

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Invasive aspergillosis with polyarthritis

Cited by 17 publications

References 13 publications

Aspergillus arthritis and organ transplantation

Aspergillus arthritis and organ transplantation

Disseminated Aspergillus flavus following septic arthritis in an immunocompetent patient: a case report

Fungal infections of bone and joint

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