2021
DOI: 10.14745/ccdr.v47i11a09
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Invasive bacterial diseases in northern Canada, 1999 to 2018

Abstract: Background: The International Circumpolar Surveillance (ICS) program conducts surveillance on five invasive bacterial diseases: pneumococcal disease (IPD), group A streptococcus (iGAS), Haemophilus influenzae (Hi), meningococcal disease (IMD) and group B streptococcus (GBS). Invasive bacterial diseases have a higher burden of disease in northern populations than the rest of Canada. Methods: To describe the epidemiology of invasive bacterial diseases in northern Canada from 1999 to 2018, data for IPD, iGAS, Hi… Show more

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“…The prevalence of all H. influenzae , particularly NTHi, was significantly higher in NP specimens of children from Nunavut compared to children from Southern Ontario. Invasive H. influenzae disease is also much more common in children from Northern Canada, including Nunavut, than in the whole province of Ontario, illustrated by recently reported incidence rates of 195.15/100,000 versus 10.17/100,000 for <1-year old, respectively [ 19 , 20 ]. Moreover, the serotype distribution of invasive H. influenzae isolates differs strikingly between the regions, with Hia greatly offsetting NTHi in the North (60.5% Hia and 17.8% NTHi), in contrast to Ontario where NTHi predominates (8.9% Hia and 74.2%, NTHi) [ 19 , 20 ].…”
Section: Discussionmentioning
confidence: 99%
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“…The prevalence of all H. influenzae , particularly NTHi, was significantly higher in NP specimens of children from Nunavut compared to children from Southern Ontario. Invasive H. influenzae disease is also much more common in children from Northern Canada, including Nunavut, than in the whole province of Ontario, illustrated by recently reported incidence rates of 195.15/100,000 versus 10.17/100,000 for <1-year old, respectively [ 19 , 20 ]. Moreover, the serotype distribution of invasive H. influenzae isolates differs strikingly between the regions, with Hia greatly offsetting NTHi in the North (60.5% Hia and 17.8% NTHi), in contrast to Ontario where NTHi predominates (8.9% Hia and 74.2%, NTHi) [ 19 , 20 ].…”
Section: Discussionmentioning
confidence: 99%
“…Invasive H. influenzae disease is also much more common in children from Northern Canada, including Nunavut, than in the whole province of Ontario, illustrated by recently reported incidence rates of 195.15/100,000 versus 10.17/100,000 for <1-year old, respectively [ 19 , 20 ]. Moreover, the serotype distribution of invasive H. influenzae isolates differs strikingly between the regions, with Hia greatly offsetting NTHi in the North (60.5% Hia and 17.8% NTHi), in contrast to Ontario where NTHi predominates (8.9% Hia and 74.2%, NTHi) [ 19 , 20 ]. In Ontario children <1 year of age, in 2014–2018, the incidence rates of invasive disease caused by Hia and NTHi were 2.79/100,000 and 5.85/100,000, respectively [ 20 ].…”
Section: Discussionmentioning
confidence: 99%
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