2014
DOI: 10.1186/1471-2334-14-327
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Invasive candidiasis in low birth weight preterm infants: risk factors, clinical course and outcome in a prospective multicenter study of cases and their matched controls

Abstract: BackgroundThis multicenter prospective study of invasive candidiasis (IC) was carried out to determine the risk factors for, incidence of, clinical and laboratory features, treatment and outcome of IC in infants of birth weight <1250 g.MethodsNeonates <1250 g with IC and their matched controls (2:1) were followed longitudinally and descriptive analysis was performed. Survivors underwent neurodevelopmental assessment at 18 to 24 months corrected age. Neurodevelopmental impairment (NDI) was defined as blindness,… Show more

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Cited by 72 publications
(49 citation statements)
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“…[1] In our patient C. albicans grew in blood and urine, but no other organ system was involved. Observed hyperglycaemia can be interpreted as a marker for invasive fungal infection.…”
Section: Discussionmentioning
confidence: 60%
See 1 more Smart Citation
“…[1] In our patient C. albicans grew in blood and urine, but no other organ system was involved. Observed hyperglycaemia can be interpreted as a marker for invasive fungal infection.…”
Section: Discussionmentioning
confidence: 60%
“…[1] Patients typically present on the first day of life (DOL) with skin lesions of various morphologies. A progression to systemic candida infection occurs in up to 50% of CCC cases in extremely low birth weight (ELBW) infants.…”
Section: Introductionmentioning
confidence: 99%
“…İK'te en önemli olan durum çoklu organ ve sistemlerin tutulumu olup özellikle ÇDDA bebeklerde çoklu organ yetmezliğinde prognoz iyi değildir. En sık tutulan organlar; göz, üriner sistem, kalp ve santral sinir sistemi olup, her bir organ ve sistem muayene edilmelidir (26). Tek bir kan kültürü pozitifliği varlığında bile yaygın enfeksiyon gelişmiş olabilmektedir (25).…”
Section: Sistemik Enfeksiyonlarunclassified
“…CLABSIs per 1000 central line-days reduced from 0.9 in 1999 to 0.2 in 2009; p < 0.001) [12]. However, the mortality rate associated with invasive candidiasis is reported to range from 19.6% to 63% and remains a major concern [1,4,13].…”
mentioning
confidence: 99%