Invasive Fungal Infections in Living Unrelated Renal Transplantation

Alkhunaizi, Ahmed M.; Amir, Abdulrazack; Al‐Tawfiq, Jaffar A.

doi:10.1016/j.transproceed.2005.07.029

Cited by 16 publications

(21 citation statements)

References 17 publications

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“…In agreement with the previous reports [7][8][9][10][11][12][13] (Table 1) where all patients presented with pyrexia and graft dysfunction-due to combined graft rejection and mucormycosis; our patient also presented with prolonged pyrexia, graft dysfunction-due to acute rejection-associated with ethimoidal sinus mucormycosis and had survived after combined antifungal and aggressive anti-rejection therapies. The last case reported by Ahmed [14] showed that aggressive anti-rejection therapy with methylprednisolone and antithymocyte globulin seemed to contribute to the unfavorable outcome of his case.…”

Section: Discussionsupporting

confidence: 92%

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Successful treatment of mucormycosis in a renal allograft recipient

et al. 2008

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Section: Discussionsupporting

confidence: 92%

“…Alkhaunaizi et al [13] reported three cases that underwent living unrelated renal allotransplantation and developed systemic fungal infections. The first patient developed disseminated mucomycosis, the second developed invasive aspergillosis, and the third developed central nervous system infection.…”

Section: Discussionmentioning

confidence: 99%

Successful treatment of mucormycosis in a renal allograft recipient

et al. 2008

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“…Cerebral phaeohyphomycosis is an infection caused by dematiaceous fungi especially in immunocompromized patients [1][2][3]. Of the dematiaceous fungi known to be neurotrophic include Cladophialophora bantiana, Wangiella dermatitidis and Chaetomium atrobrunneum [4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

“…Of the dematiaceous fungi known to be neurotrophic include Cladophialophora bantiana, Wangiella dermatitidis and Chaetomium atrobrunneum [4][5][6][7]. In addition, Rhinocladiella mackenziei (formerly Ramichloridium mackenziei) has been reported to be a causative agent of fatal cases of R. mackenziei infection [1][2][3]. R. mackenziei infection appears to occur predominantly in the Middle East and to target the brain exclusively [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

“…In addition, Rhinocladiella mackenziei (formerly Ramichloridium mackenziei) has been reported to be a causative agent of fatal cases of R. mackenziei infection [1][2][3]. R. mackenziei infection appears to occur predominantly in the Middle East and to target the brain exclusively [1][2][3]. However, it should be noted that R. mackenziei has not been recovered from any environmental source [3].…”

Section: Introductionmentioning

confidence: 99%

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Cerebral phaeohyphomycosis due to Rhinocladiella mackenziei (formerly Ramichloridium mackenziei): Case presentation and literature review

Al‐Tawfiq

Boukhamseen

2011

Journal of Infection and Public Health

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Summary Rhinocladiella mackenziei (formerly Ramichloridium mackenziei), a causative agent of cerebral phaeohyphomycosis, is extremely rare and it is geographically limited to the Middle East. The organism has a predilection to cause brain infections and results in a grave prognosis with a high mortality rate. The current patient was admitted to a long term care facility with chronic respiratory failure and dependence on a mechanical ventilator. She later developed left sided weakness and a CT-scan of the brain revealed multiple variable sized hypodense, well-defined lesions with ring enhancement. A stereotactic needle aspiration of the largest lesion showed fungal hyphae. The final culture grew R. mackenzie. The patient was initially started on liposomal amphotericin B, then voriconazole and caspofungin intravenously as posaconazole was not available. The patient failed to respond to antifungal therapy and finally she died 34 days after the start of the treatment. R. mackenziei is a highly virulent agent, and should be considered in the differential diagnosis of central nervous system disease in patients from the Middle East.

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Pyelo-ureteral necrosis after renal transplantation

Spasovski¹,

Masin-Spasovska²,

Stavridis³

et al. 2008

Int Urol Nephrol

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Because of the limited chance of receiving a kidney transplant (for several well-known reasons), a lot of desperate dialysis patients procure an unrelated donor kidney transplant against all medical advice. This type of renal paid transplantation is associated with many surgical complications and invasive opportunistic infections that increase the morbidity and mortality in this group of transplant recipients. In this report, we describe a case of a 22-year-old girl with a segmental infarction of the graft lower pole and a complete pyelo-ureteral necrosis as a consequence of some vascular damage, complicated by a pathohistological finding of an invasive candidiasis. Despite the successful surgical pyelovesical anastomosis and the good recovery of the patient and the kidney, long-term prognosis remains poor. The lack of information from the transplanting center regarding both donor and recipient and the associated, unacceptable risks on the graft and patient survival in unrelated, paid transplant recipients reinforce the standpoint that this practice should be abandoned.

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Invasive Fungal Infections in Living Unrelated Renal Transplantation

Cited by 16 publications

References 17 publications

Successful treatment of mucormycosis in a renal allograft recipient

Successful treatment of mucormycosis in a renal allograft recipient

Cerebral phaeohyphomycosis due to Rhinocladiella mackenziei (formerly Ramichloridium mackenziei): Case presentation and literature review

Pyelo-ureteral necrosis after renal transplantation

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