Invasive lobular breast carcinoma metastasising to the rectum

Abstract

Gastrointestinal (GI) metastasis from a primary breast carcinoma is uncommon, with the rectum being one of the least reported sites in the literature. We report a case of a 79-year-old woman who underwent treatment for an infiltrative lobular carcinoma of the right breast with nodal involvement, and 10 years later developed recurrence in the form of rectal metastasis. Spread to the GI tract is most commonly seen with lobular breast carcinomas. Any patient with a history of breast cancer presenting typically or atypically with abdominal symptoms or altered bowel habit should raise a high index of suspicion for recurrent or metastatic disease.

Anorectal metastasis from breast carcinoma: a case report and review of the literature

“…Our patient had progressive bone metastases, peritoneal involvement was seen during laparoscopy and later on a suspect gastric lesion was found. Average survival after diagnosis of GI metastases is 1–2 years [ 6 , 10 , 14 ].…”

“…It occurs only in less than 1% of all metastatic cases and the metastatic rate is higher for ILC than for ductal adenocarcinoma. In the GI tract, the stomach is the most commonly affected organ, metastatic spread to the rectum and anal region is extremely rare [ 4 – 6 ].…”

Rectal Metastases of Breast Carcinoma: A Case Report

“…Metastasis to the gastrointestinal (GI) tract is uncommon, mainly if breast is the primary site; clinical manifestations are usually non-specific with symptoms related to local factors and extension of the bowel involvement. [1][2][3][4][5][6][7][8][9] Breast cancer affects lymph nodes, bones, lungs, liver, brain, and soft tissues, but rectal spread is very rare. [2][3][4][5][6][7][8][9] Lobular carcinoma is a major subtype in GI implants with up to 18% of incidence.…”

“…[1][2][3][4][5][6][7][8][9] Breast cancer affects lymph nodes, bones, lungs, liver, brain, and soft tissues, but rectal spread is very rare. [2][3][4][5][6][7][8][9] Lobular carcinoma is a major subtype in GI implants with up to 18% of incidence. 1,2,[4][5][6][7][8][9] The period between the primary tumor diagnosis and evidence of implants is variable and reported to be up to 30 years.…”

“…[2][3][4][5][6][7][8][9] Lobular carcinoma is a major subtype in GI implants with up to 18% of incidence. 1,2,[4][5][6][7][8][9] The period between the primary tumor diagnosis and evidence of implants is variable and reported to be up to 30 years. 1,4,8,9 The diagnosis of breast cancer ocasionally occurs after manifestations of the rectal metastases.…”