Invasive Mole with Nephrotic Syndrome: A Case Report with Literature Review

Abstract

Invasive mole (IM), a malignant tumor, is a form of gestational trophoblastic neoplasia (GTN), which are characterized by invasive hydatid tissue into the myometrium or distant metastasis [1]. The most common transfer locations for IM are the vagina, lungs and brain. The most common symptom of IM is irregular vaginal bleeding, but further symptoms caused by bleeding in the metastases may also be detected, such as hemoptysis and neurological symptoms [2]. Myometrial invasion, swollen villi and hyperplastic trophoblast are often considered to be the pathological features of IM. IM′s clinical diagnosis mainly depends on medical history, clinical symptoms, laboratory tests and examination using imaging. Pathological results are the most essential basis for diagnosis. Good prognosis based on timely and comprehensive chemotherapy [3]. In this report, we describe a patient presenting with NS in which the underlying diagnosis of IM was made by a combination of chance and a high level of clinical suspicion, and to improve patient care amongst internists by heightening awareness of this uncommon condition.