Invasive Squamous Cell Carcinoma of the Cervix in Pregnancy: A Case Report

Abstract

Cervical squamous cell carcinoma is the most common histological type of carcinoma in the uterine cervix, but during pregnancy is relativity uncommon, with an incidence of 0.8 to 1.5 cases per 10,000 births. Cervical squamous cell carcinoma is the leading cause of death among women aged 35 to 54 years and the second most common cause among women aged 15 to 34 years after breast carcinoma. Most patients are diagnosed at an early stage of the disease, probably due to routine prenatal screening. The occurrence of invasive cervical carcinoma is relatively uncommon in pregnant women. However, cancer treatment during pregnancy currently remains one of the main and biggest therapeutic challenges in cervical cancer. The therapeutic approach should be customized and depends mainly on histology, disease stage, and gestational age. We present a case concerning a 26-year-old woman with invasive moderately differentiated keratinizing squamous cell cervical carcinoma, stage pT2b, N1, M0/ FIGOIIB, during pregnancy (4th lunar month).