Invasive Thymoma With Endobronchial Metastasis

Benton, Stewart M.; Rogers, Raford P.; Reed, Carolyn E.

doi:10.1016/j.athoracsur.2009.06.118

Cited by 6 publications

(7 citation statements)

References 6 publications

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“…Nineteen of these 20 patients had shown symptoms of shortness of breath, and one patient had no symptom. The mass directly infiltrated or appeared through hematogenous or lymphangitic metastasis, and there were more invasions in the left bronchial tree than in the right2-4. However, there have been no case reports of invasive thymoma that showed polypoid proliferation by infiltrating only the trachea without invading the lung or blood vessels, as seen in this case.…”

Section: Discussionmentioning

confidence: 65%

“…Although invasive thymoma, which progresses locally at times, applies pressure to the trachea, there has been no report yet of its invasion of trachea through the proliferation of polypoid tumors. Up to the present, however, there have been 20 cases all over the world of invasive thymoma with endobronchial polypoid growth2-4. The authors have experienced a case of invasive thymoma with endotracheal polypoid growth and have successfully treated it.…”

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confidence: 99%

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A Case of Invasive Thymoma with Endotracheal Polypoid Growth

et al. 2012

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Thymomas are one of the most common neoplasms of the mediastinum derived from thymic epithelium. It is common that invasive thymoma invades the lung, pericardium, and great vessels. Airway compression by mass effect also occurs, but direct polypoid tumor growth into the airway is extremely rare. Only 20 cases of invasive thymoma with endobronchial polypoid growth have previously been reported globally. However, there is no case report of invasive thymoma with endotracheal growth. Herein, we report a rare case of invasive thymoma with endotracheal polypoid growth in a 28-year-old woman.

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Section: Discussionmentioning

confidence: 65%

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confidence: 99%

A Case of Invasive Thymoma with Endotracheal Polypoid Growth

et al. 2012

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“…Thymomas are rare epithelial neoplasms that constitute approximately 15% of all mediastinal masses and 50% of primary tumors of the anterior mediastinum [1]. Some forms of thymoma are invasive and can have extension to the mediastinum and all neighboring structures.…”

Section: Discussionmentioning

confidence: 99%

“…Thymomas are one of the most common neoplasms of the mediastinum. It represents approximately 15% of all mediastinal masses and 50% of primary tumors of the anterior mediastinum [1]. It may demonstrate invasion of contiguous mediastinal structures (pleura, pericardium, or other mediastinal structures).…”

Section: Introductionmentioning

confidence: 99%

Invasive Thymoma with Endobronchial Polypoid Growth

Àouadi¹,

Braham²,

Ayadi³

et al. 2015

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Thymomas are the most common neoplasms of the mediastinum. It is common that thymoma invades neighboring structures in the thorax, but direct polypoid tumor growth into the airway is extremely rare. We report a rare case of invasive thymoma with polypoid endobronchial growth in a 66-year-old woman. Computed tomography demonstrated an anterior mediastinal tumor which extended into the right upper lobe. Endoscopic examination revealed a polypoid tumor which occluded the right upper bronchus. A biopsy specimen obtained from the intraluminal mass was very suggestive of thymoma. The patient had no parathymic syndrome. The tumor was resected with the right upper lobe. The final post-operative tissue findings confirmed a type B2 thymoma of the World Health Organisation classification.

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“…9 In human beings, EBM has been reported in association with carcinomas of the breast, urinary bladder, prostate, and gastrointestinal tract (specifically colon) and is more rarely documented with sarcomas. [1][2][3][4]6,7,[13][14][15] Expectoration of airway casts containing neoplastic cells from EBM lesions may precede the diagnosis of the primary tumor or occur several years after treatment of a primary tumor. 3,8,9,11,12 Findings of computed tomography imaging include atelectasis and obstruction or narrowing of airways adjacent to a pulmonary mass, but do not always demonstrate the intramural nature of the lesions; the latter is often identified by bronchoscopy or histology following surgical resection of the tumor.…”

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confidence: 99%

Endobronchial metastasis in a dog with sarcoma

2013

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A 3-year-old neutered male Australian Shepherd mix dog presented with metastatic soft tissue sarcoma arising from a primary tumor in the left lumbar fascia. Two separate metastases to the lungs were characterized by neoplasia within bronchiolar walls, which caused obstruction of the bronchiolar lumina and atelectasis of adjacent alveoli, a characteristic feature of endobronchial metastasis. Neoplastic cells of the primary lumbar neoplasm, metastatic pulmonary lesions, and additional widespread metastatic masses identified postmortem were similarly immunoreactive for vimentin, but non-immunoreactive for cytokeratin, cluster of differentiation 18, synaptophysin, chromogranin, and desmin. The present report describes a naturally occurring case of endobronchial metastasis in a dog.

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Invasive Thymoma With Endobronchial Metastasis

Cited by 6 publications

References 6 publications

A Case of Invasive Thymoma with Endotracheal Polypoid Growth

A Case of Invasive Thymoma with Endotracheal Polypoid Growth

Invasive Thymoma with Endobronchial Polypoid Growth

Endobronchial metastasis in a dog with sarcoma

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