Inverse Correlation Between Coffee Consumption and Prevalence of Metabolic Syndrome: Baseline Survey of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study in Tokushima, Japan

Abstract

BackgroundIt is unclear whether consumption of coffee and green tea is associated with metabolic syndrome.MethodsThis cross-sectional study enrolled 554 adults who had participated in the baseline survey of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study in Tokushima Prefecture, Japan. Consumption of coffee and green tea was assessed using a questionnaire. Metabolic syndrome was diagnosed using the criteria of the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) and the Japan Society for the Study of Obesity (JASSO). Logistic regression analysis was used to examine the association between consumption of coffee and green tea and prevalence of metabolic syndrome and its components.ResultsAfter adjustment for sex, age, and other potential confounders, greater coffee consumption was associated with a significantly lower prevalence of metabolic syndrome, as defined by NCEP ATP III criteria (P for trend = 0.03). Participants who drank more coffee had a lower odds ratio (OR) for high serum triglycerides (P for trend = 0.02), but not for increased waist circumference or high blood pressure. Using JASSO criteria, moderate coffee consumption (1.5 to <3 cups/day) was associated with a significantly lower OR for high plasma glucose (OR = 0.51, 95% CI 0.28-0.93). Green tea consumption was not associated with the prevalence of metabolic syndrome or any of its components.ConclusionsCoffee consumption was inversely correlated with metabolic syndrome diagnosed using NCEP ATP III criteria, mainly because it was associated with lower serum triglyceride levels. This association highlights the need for further prospective studies of the causality of these relationships.

Coffee polyphenol consumption improves postprandial hyperglycemia associated with impaired vascular endothelial function in healthy male adults

“…Many studies have demonstrated the potential health benefits of daily coffee consumption. Previous epidemiological studies have reported that an increase in daily consumption of coffee was associated with a reduced risk of metabolic syndrome [1][2][3], diabetes [4], and death due to cardiovascular diseases [5]. Similar findings were also true for decaffeinated coffee consumption [6].…”

Coffee consumption and risk of the metabolic syndrome: A meta-analysis

“…One study [37] reported an RR > 1 with 95% CI that did overlap 1.0, while six studies [23][24][25][26]36,39] reported RRs < 1 and 95% CIs not overlapping 1.0. The remaining four studies [27,28,37,39] reported RRs < 1 and 95% CIs overlapping 1.0.…”

“…In all, 41 full-text articles were reviewed, with 30 articles excluded because: one was a review; one had duplicate data; and 28 had no reported RRs or 95% CIs for the relationship between coffee intake and MetS. Finally, 11 published articles [23][24][25][26][27][28][35][36][37][38][39], including 13 studies with a total of 159,805 participants, were identified as eligible for the present meta-analysis of the relationship between coffee consumption with MetS risk. Of these, two articles [37,39] included two studies each; four studies were cohort studies with a total of 106,855 participants; eight studies were cross-sectional studies with 52,700 participants; and one was a case-control study with 250 participants.…”

“…In the dose-response analysis, data came from four articles [25,36,37,39] and included a total of 95,398 subjects. Evidence of a non-linear association was found (P non-linearity < 0.001) between coffee consumption and risk of MetS (Fig.…”

Association between the Prevalence of Metabolic Syndrome and the Level of Coffee Consumption among Korean Women

“…[3] Some previous studies have suggested the potential association between coffee intake and the risk of metabolic syndrome. [4–6]…”