Inverse correlation of each functional status scale of the SF-36 with degree of disease activity in systemic lupus erythematosus (m-SLAM)

Saba, Jihan; Quinet, Robert; Davis, William E.; Krousel‐Wood, Marie; Chambers, Richard; Gomez, Natalie Nunez; Serebro, Leonard; Nair, P. K. R.

doi:10.1016/s1297-319x(03)00065-4

Cited by 33 publications

(25 citation statements)

References 4 publications

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“…Many studies have found no correlation between the SF-36 and disease activity (12,15,16). Others have found a relationship between the SF-36 and disease activity using the Systemic Lupus Activity Measure, or British Isles Lupus Assessment Group (18,24,25). Our study of patients with longstanding disease with low disease activity demonstrates that the majority of quality of life domains, as measured by the SF-36, do not change over time.…”

Section: Discussionmentioning

confidence: 99%

“…However, inconsistent results have been reported regarding the influence of disease activity and damage on quality of life. Some studies have demonstrated a lack of correlation among these outcomes while others have shown disease variables to be strong predictors of quality of life (12)(13)(14)(15)(16)(17)(18). A recent review of quality of life in SLE concluded that there was no correlation with disease activity or damage (19).…”

Section: Introductionmentioning

confidence: 99%

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Quality of life over time in patients with systemic lupus erythematosus

Kuriya¹,

Gladman²,

Ibanez³

et al. 2008

Arthritis & Rheumatism

134

108

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Objective. To determine whether quality of life in patients with systemic lupus erythematosus (SLE) measured by the Short Form 36 (SF-36) changes over time and which patient-and disease-related factors influence such change. Methods. SLE patients who had >6 SF-36 evaluations during followup were identified from a database. Outcomes were slopes of scores of the 8 SF-36 domains as well as the physical and mental component scores. Based on the direction of the slope, patients were designated as unchanged, improved, or worsened. Linear regression models were used to test the contribution of risk factors to slopes. Nonparametric tests were used to evaluate risk factors between patterns of clinical change. Results. A total of 146 patients had >6 SF-36 evaluations in 1,047 visits over a mean ؎ SD period of 8.2 ؎ 1.1 years. During the interval, the majority of patients showed no change in the SF-36 domains and only a small minority demonstrated improvement. Physical and mental component scores were unchanged in 84.3% and 87.7% of patients whereas 4.1% and 7.5% improved, respectively. According to slopes of the domains and summary scores, only physical functioning demonstrated a significant decrease over time. There were no lupus disease features associated with decline in physical functioning except for the presence of fibromyalgia. Conclusion. The SF-36 in SLE patients with established disease changed little over an 8-year period. Changes in the SF-36 were not affected by disease activity, steroids, or damage accumulation during the interval, but were affected by the presence of fibromyalgia.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Quality of life over time in patients with systemic lupus erythematosus

Kuriya¹,

Gladman²,

Ibanez³

et al. 2008

Arthritis & Rheumatism

134

108

View full text Add to dashboard Cite

show abstract

“…We chose a score of 10, on the basis of the distribution of the scores for patients otherwise considered to have moderate or marked disease activity as per the doctor's global assessment of disease activity 12 rather than a lower score. 59 Also, an instrument that assesses disease activity by organ system (such as the British Isles Lupus Assessment Group Index) may have been more appropriate for our analyses. 60 Unfortunately, we did not collect the clinical information necessary to score the BILAG in our patients.…”

Section: Discussionmentioning

confidence: 99%

Systemic lupus erythematosus in a multiethnic cohort: LUMINA XXXV. Predictive factors of high disease activity over time

Alarcón

Calvo‐Alén

McGwin³

et al. 2006

Annals of the Rheumatic Diseases

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“…22 More recently, the LupusQoLß has been adapted and validated for the assessment of patients with SLE in the United States (LupusQoLß-US) and for Spanish-speaking populations. 27,28 Some studies have evaluated the validity of the LupusQoLß and its correlation with disease activity. 22,27 A recent cross-sectional study has shown that HRQOL is impaired in SLE patients and, more importantly, no association was found between the eight domains of the LupusQoLß and clinical or demographic variables.…”

Section: Introductionmentioning

confidence: 99%

Health related quality of life in Mexican women with systemic lupus erythematosus: a descriptive study using SF-36 and LupusQoL©

Garcı́a-Carrasco

Cardiel²,

Méndez‐Martínez

et al. 2012

Lupus

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The LupusQoL© questionnaire is a disease-specific health related quality of life (HRQOL) instrument for adults with systemic lupus erythematosus (SLE). The Short Form-36 (SF-36) is a generic instrument that captures the physical, psychological, and social impact. We conducted a descriptive study of women aged ≥ 18 years attending our Lupus Clinic. HRQOL was assessed by applying the LupusQoL© and SF-36. Lupus activity was measured using the Mexican Systemic Lupus Erythematosus Disease Activity Index (Mex-SLEDAI) and chronic damage using the Systemic Lupus Collaborative Clinics Damage Index (SDI). Data were analyzed using descriptive statistics, the chi-square test and Pearson's product moment correlation coefficient. A total of 127 patients were included with a mean age of 40.5 ± 12.6 years. The mean disease duration was 8.2 ± 5.6 years, the mean disease activity score was 2.4 ± 3.0, and the mean SDI score 0.77 ± 1.06. The mean SF-36 score was 58.1 ± 21.1 and the mean LupusQoL© score was 69 ± 22.7. The correlation between global scores of the SF-36 and LupusQoL© was rho = 0.73 (p < 0.001). The correlation between lupus disease activity and the SF-36 and the LupusQoL© was -0.26 (p = 0.003) and -0.25 (p = 0.004), respectively. The correlation between the SDI and the SF-36 and the LupusQoL© was -0.28 (p = 0.001) and -0.38 (p < 0.0001), respectively. In conclusions: both LupusQoL© and SF-36 were useful instruments in assessing HRQOL in Mexican lupus female patients. The usefulness of the LupusQoL© should be evaluated in lupus patients with moderate to severe disease activity.

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Inverse correlation of each functional status scale of the SF-36 with degree of disease activity in systemic lupus erythematosus (m-SLAM)

Cited by 33 publications

References 4 publications

Quality of life over time in patients with systemic lupus erythematosus

Quality of life over time in patients with systemic lupus erythematosus

Systemic lupus erythematosus in a multiethnic cohort: LUMINA XXXV. Predictive factors of high disease activity over time

Health related quality of life in Mexican women with systemic lupus erythematosus: a descriptive study using SF-36 and LupusQoL©

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