A Carleman estimate and the unique continuation property of solutions for a multi-terms time fractional diffusion equation up to order α (0 < α < 2) and general time dependent second order strongly elliptic time elliptic operator for the diffusion. The estimate is derived via some subelliptic estimate for an operator associated to this equation using calculus of pseudo-differential operators. A special Holmgren type transformation which is linear with respect to time is used to show the local unique continuation of solutions. We developed a new argument to derive the global unique continuation of solutions. Here the global unique continuation means as follows. If u is a solution of the multiterms time fractional diffusion equation in a domain over the time interval (0, T ), then a zero set of solution over a subdomain of Ω can be continued to (0, T ) × Ω.