2012
DOI: 10.1007/s13555-012-0015-5
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Inverse Psoriasis Involving Genital Skin Folds: Successful Therapy with Dapsone

Abstract: IntroductionInverse psoriasis is a rare form of psoriasis that affects between 3% and 7% of the patients with psoriasis. It can comprise genital skin folds as part of genital psoriasis, and it is one of the most commonly seen dermatoses of this area. There are few evidence-based studies about the treatment of intertriginous psoriasis involving genital skin folds.Case PresentationThe authors present a 42-year-old female patient with erythematous plaques in the vulva, groin, and perianal region. The patient had … Show more

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Cited by 38 publications
(35 citation statements)
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“…Treatment of the sensitive genital skin is challenging, because of the unique genital environment (warmth, moisture and exposure to friction) [26]. Moreover, a suitable choice of remedies is necessary to avoid irritation in this area.…”
Section: Treatmentmentioning
confidence: 99%
See 1 more Smart Citation
“…Treatment of the sensitive genital skin is challenging, because of the unique genital environment (warmth, moisture and exposure to friction) [26]. Moreover, a suitable choice of remedies is necessary to avoid irritation in this area.…”
Section: Treatmentmentioning
confidence: 99%
“…Phototherapy and laser therapy are not recommended in the genital area [34]. In sporadic cases, complete remission of genital psoriasis was documented after four weeks of treatment with oral dapsone (100 mg once a day) [6,26]. Psoriasis treatment in pregnant women is a challenge and both mother's and foetal health should be taken into consideration, when choosing a drug regimen.…”
Section: Treatmentmentioning
confidence: 99%
“…Generell sollten die folgenden allgemeinen Faktoren berücksichtigt werden, um die Ausprä-gung und das Milieu der betroffenen intertriginösen Areale positiv zu beeinflussen: 4 Topische Glukokortikosteroide mit einem therapeutischen Index von 2,0, also einem positiven Nutzen-Risiko-Verhältnis, sind zu bevorzugen (. Tab.…”
Section: Therapieunclassified
“…Anwendung von Dapson bei Psoriasis inversa vor[4]. Dies kann zum jetzigen Zeitpunkt aber nicht empfohlen werden.…”
unclassified
“…5 Today, oral dapsone is used as a primary or adjuvant therapy in many rare and refractory dermatological conditions (Table 1). 2,3,6 Figure 1. Chemical structure of dapsone, a sulfone.…”
mentioning
confidence: 99%