Inverted ratio of inducer to suppressor T-lymphocyte subsets in drug abusers with opportunistic infections

Moll, Bernice; Emeson, Eugene E.; Small, Catherine B.; Friedland, Gerald; Klein, Robert S.; Spigland, Ilya

doi:10.1016/0090-1229(82)90206-9

Cited by 42 publications

(9 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The percentage of helper/inducer T cells, suppressor/cytotoxic T cells, and helper/suppressor-cell ratios were determined using the monoclonal antibodies OKT-4 and OKT-8, respectively (Ortho), as previously described (Moll et al, 1982).…”

Section: T-lymphocyte Subset Assaymentioning

confidence: 99%

Modulation of cellular immunity in medical students

et al. 1986

View full text Add to dashboard Cite

show abstract

Section: T-lymphocyte Subset Assaymentioning

confidence: 99%

Modulation of cellular immunity in medical students

et al. 1986

View full text Add to dashboard Cite

show abstract

“…Antibody to, regression associated with, and secretion in saliva of EB virus in patients with(1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) and without(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25) lymphadenopathy Titres of IgG antibody to:…”

mentioning

confidence: 99%

Epstein-Barr (EB) virus infection in homosexual men in London.

Crawford¹,

Weller²,

Iliescu³

et al. 1984

Sexually Transmitted Infections

View full text Add to dashboard Cite

“…In adults, AIDS is mainly seen in young homosexual or bisexual males [10], their female sexual partners [12], drug abusers [14], prisoners [26], Haitians [24], patients transfused with blood products [3] and haemophiliacs having had multiple factor VIII infusions [17]. Recently, AIDS has been diagnosed in black African immigrants in Europe [5,21].…”

Section: Discussionmentioning

confidence: 99%

AIDS in two African children—one with fibrosarcoma of the liver

et al. 1985

View full text Add to dashboard Cite

We report here on two black African girls who developed an acquired immune deficiency syndrome (AIDS). The first patient was a premature girl born to healthy parents. She suffered from interstitial pneumonitis during the first week of life and died of it at the age of 6 months. Her mother, although asymptomatic, had polyclonal hypergammaglobulinaemia, a reversed T-helper/T-suppressor ratio and a decreased lymphocyte response to mitogens. The second patient had the first symptoms at the age of 6 years, developed a primitive malignant fibrosarcoma of the liver at 8 years old and died 1 year later. AIDS can affect black African children who have not been transfused and whose family members are not considered as at a high risk for this disease. In children, AIDS and cancer can be associated. In the second patient, cytotoxic suppressor lymphocytes (OKT8 positive cells) were shown to behave in vitro as precursors of T-killer cells.

show abstract

Inverted ratio of inducer to suppressor T-lymphocyte subsets in drug abusers with opportunistic infections

Cited by 42 publications

References 20 publications

Modulation of cellular immunity in medical students

Modulation of cellular immunity in medical students

Epstein-Barr (EB) virus infection in homosexual men in London.

AIDS in two African children—one with fibrosarcoma of the liver

Contact Info

Product

Resources

About