Investigating acoustic startle habituation and prepulse inhibition with silent functional MRI and electromyography in young, healthy adults
Laura F. Naysmith,
Owen O’Daly,
Ana Beatriz Solana
et al.
Abstract:IntroductionStartle habituation and prepulse inhibition (PPI) are distinct measures of different sensory information processes, yet both result in the attenuation of the startle reflex. Identifying startle habituation and PPI neural mechanisms in humans has mostly evolved from acoustic-focused rodent models. Human functional magnetic resonance imaging (fMRI) studies have used tactile startle paradigms to avoid the confounding effects of gradient-related acoustic noise on auditory paradigms and blood-oxygen-lev… Show more
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