Investigating the Effect of Injectable Ozone in Treating Symptoms and Improving Performance in Patients with Tennis Elbow Disease

Abstract

Check for updateselbow. Overuse of the wrist in gripping and extension is the accepted etiology for LE [1]. This condition is not only a causes of pain, but it also plays a key role to loss of function at the elbow joint. As the result, reduction of normal activity and absence from work is possible. Conservative treatments such as nonsteroidal anti-inflammatory drugs (NSAIDs), ice, rest, and reducing motion are required for settling the pain and inflammation [2]. A systematic review conducted by Bateman, et al. showed that surgical interventions in LE patients are not more effective than nonsurgical treatments [3].Local corticosteroid injection is a safe way to manage pain in LE. Smidt, et al. found a significant short-term reduction in pain and grip strength after corticosteroid injection compared to placebo, local anesthetics, or conservative treatments [4], however, long-term changes were not significant. In addition, corticosteroid injection was significantly better than placebo and naproxen in a clinical trial [5]. On the other hand, a study compared corticosteroid and ozone injection in a clinical trial and found better outcomes following ozone injection [6]. The safety of ozone therapy in LE is not established yet in the literature, however, there is no strong evidence of harm in this treatment method [7]. In this communication, we aimed to compare the severity of pain, tenderness, and involved elbow before and after the ozone injection treatment regimen in LE.