The most basic axis of a society’s economic and social growth is health, and social capital is a major factor in determining that development. The purpose of this research was to evaluate, among the student body of Iran University of Medical Sciences, the connection that exists between social capital and overall health. This study used a descriptive-analytical approach to cross-sectional research. Students attending the Iran University of Medical Sciences constituted the statistical population. The approach developed by Cochran was used to pick 367 students at random. The demographic information form, two versions of the Delaviz Social Capital Questionnaire (2006), and Goldberg and Hiller’s General Health Questionnaire (1979), served as the data collection tools. Using Cronbach’s alpha test, the reliability of the first two sets of questionnaires was determined to be 0.73 and 0.78, respectively. The data were analyzed using descriptive statistics, statistical tests, and regression after being loaded into SPSS version 22. It was shown that general health was significantly related to the factors of gender, location of living, and degree of education (<i>p</i> < 0.05). It was shown via the use of regression that there is a statistically significant association between social capital and the two dimensions of group involvement and relationships in networks. These two dimensions had the biggest influence on general health and explained 39% of its variations. The overall health of students was not significantly affected by factors such as age, educational level, or marital status (<i>p</i> > 0.05). It is feasible to improve students’ overall health if social capital is increased, more students are encouraged to participate in group projects, and students’ ties with one another inside and outside their networks are expanded.