This chapter is dedicated to equipping practitioners with a comprehensive set of strategies that not only foster inclusive environments but also support student engagement and well-being. It seeks to encourage collaborative partnerships with families and colleagues, emphasizing the value of trust and cultivating a supportive classroom culture. The chapter places a strong emphasis on respecting diversity, integrating cultural considerations into the fabric of relationship building, and ensuring it is culturally responsive and respectful. It recognizes and honors the diverse backgrounds and experiences of all students and families but with a primary focus on students with disabilities (SWDs). This chapter serves as a guide for practitioners to develop effective communication, individualized instruction, and a foundation of trust because it is through the collective efforts of relationship building, supported by ongoing professional development, that practitioners can facilitate not only academic growth but also a nurturing and inclusive environment for SWDs.