Investigating the effects of exposure to extremely low frequency electromagnetic fields on job burnout syndrome and the severity of depression; the role of oxidative stress

Hosseinabadi, Majid Bagheri; Khanjani, Narges; Ebrahimi, Mohammad Hossein; Mousavi, Seyed H.; Nazarkhani, Fereshteh

doi:10.1002/1348-9585.12136

Cited by 13 publications

(9 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to some studies, ELF-EMF is the same as physiological stress and can cause oxidative stress in the brains of rats [20], chick embryonic cells and humans erythrocytes [21], and kestrel lymphocytes [22]. Numerous studies has been performed on behavior of animal which indicates that ELF-EMF are safe in some cases [23,24] but they are abundant studies declaring of hazardous effect of them in promoting anxiety and depression behaviors in animals [25][26][27] and human [28,29]. On the other hand, another research has demonstrated some anti-anxiety effects of low frequency electromagnetic fields in mice [30].…”

Section: Introductionmentioning

confidence: 99%

Maternal stress induced anxiety-like behavior exacerbated by electromagnetic fields radiation in female rats offspring

et al. 2022

View full text Add to dashboard Cite

There is a disagreement on whether extremely low frequency electromagnetic fields (ELF-EMF) have a beneficial or harmful effect on anxiety-like behavior. Prenatal stress induces frequent disturbances in offspring physiology such as anxiety-like behavior extending to adulthood. This study was designed to evaluate the effects of prenatal stress and ELF-EMF exposure before and during pregnancy on anxiety-like behavior and some anxiety-related pathways in the hippocampus of female rat offspring. A total of 24 female rats 40 days of age were distributed into four groups of 6 rats each: control, Stress (rats whose mothers underwent chronic stress), EMF (rats whose mothers were exposed to electromagnetic fields) and EMF/S (rats whose mothers were simultaneously exposed to chronic stress and ELF-EMF). The rats were given elevated plus-maze and open field tests and then their brains were dissected and their hippocampus were subjected to analysis. ELISA was used to measure 24(S)-hydroxy cholesterol, corticosterone, and serotonin levels. Cryptochrome2, steroidogenic acute regulatory protein, 3B-Hydroxy steroid dehydrogenase, N-methyl-D-aspartate receptor 2(NMDAr2) and phosphorylated N-methyl-D-aspartate receptor 2(PNMDAr2) were assayed by immunoblotting. Anxiety-like behavior increased in all treatment groups at the same time EMF increased anxiety induced by maternal stress in the EMF/S group. The stress group showed decreased serotonin and increased corticosterone levels. ELF-EMF elevated the PNMDAr2/NMDAr2 ratio and 24(S)-hydroxy cholesterol compared to the control group but did not change corticosterone. EMF did not restore changes induced by stress in behavioral and molecular tests. The results of the current study, clarified that ELF-EMF can induce anxiety-like behavior which may be attributed to an increase in the PNMDAr2/NMDAr2 ratio and 24(S)-OHC in the hippocampus, and prenatal stress may contribute to anxiety via a decrease in serotonin and an increase in corticosterone in the hippocampus. We also found that anxiety-like behavior induced by maternal stress exposure, is exacerbated by electromagnetic fields radiation.

show abstract

Section: Introductionmentioning

confidence: 99%

Maternal stress induced anxiety-like behavior exacerbated by electromagnetic fields radiation in female rats offspring

et al. 2022

View full text Add to dashboard Cite

show abstract

“…MDA, SOD, and CAT levels in the group exposed to low-frequency EMF were significantly lower than those in the nonexposed group. The prevalence of burnout syndrome and severity of depression were also higher in the former group 13 . These results suggest that oxidative stress induced by RF-EMF can lead to DNA damage in neurons during prolonged exposure to animals.…”

Section: Discussionmentioning

confidence: 83%

Impressions of the chronic 900-MHz electromagnetic field in the prenatal period on Purkinje cells in male rat pup cerebella: is it worth mentioning?

Baş

Şengül

Bas

et al. 2022

Rev. Assoc. Med. Bras.

View full text Add to dashboard Cite

OBJECTIVE:The aim of this study was to examine the changes on the Purkinje cells in the cerebella of male rat pups born to pregnant dams that were exposed to an electromagnetic field in the prenatal period. METHODS:The first stage of the study involved 12 Sprague-Dawley rats, 6 male and 6 female, weighing between 180 and 250 g. The female rats in the experimental group were exposed to a 900-MHz electromagnetic field for 1 h at the same time every day, and no procedure was performed on the control group. Following pregnancy, six male pups from each group were divided into experimental and control groups without any procedure on the pups. After 2 months, they were sacrificed and their cerebella were removed. Histopathologically, following routine processing and fixation procedures, the cerebella were embedded in the tissue blocks. The sections taken from these blocks were stained with cresyl violet. The Purkinje cells in the cerebella were then counted on sections using the optical dissector method on an image analysis system. RESULTS: The estimation of number of the Purkinje cells in the groups revealed more cells in rats in the control group than in the experimental group. Histopathologically, Purkinje cells exhibited a normal morphological structure in the control group, while the cells in the experimental group showed damage. CONCLUSIONS: It might be asserted that the exposure of mothers to an electromagnetic field in the prenatal period may affect the development of Purkinje cells in the pup cerebella.

show abstract

“…In addition, ELF-EMF-induced oxidative stress contributes to mitochondrial dysfunction. Since mitochondria plays a role in ATP generation, their dysfunction could cause energy deficit in the body and burnout syndrome 2 .…”

Section: Discussionmentioning

confidence: 99%

“…International Agency for Research on Cancer (IARC) classified ELF-EMF among probable human carcinogens (group 2B), but some studies observed a significant association between exposure to these fields and the prevalence of leukemia, breast, and brain cancer 4 . Headache, burnout, depression, anxiety, and fatigue caused by the effect of the fields on one's sleep were also reported among subjects exposed to the ELF-EMF 2 .…”

Section: Introductionmentioning

confidence: 97%

“…Nowadays, many electromagnetic waves are radiated from radar, communication equipment, cellphones, high-voltage lines, radio and television transmitters, power line columns, and electric equipment in houses and workplaces 1 . Given that job groups are exposed to these fields, one could point to power plant workers 2,3 . Although electricity is one of the basic commodities of the world and benefits of the electrical power industry are consistently increasing, public concerns about ELF-EMF exposure caused by electricity distribution have been raised 4 .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Job Stress among Workers Exposed to Extremely Low Frequency Electric and Magnetic Fields in a Combined Cycle Power Plant

Abarghoee¹,

Halvani²,

Kargar-Shouroki³

et al. 2022

JEHSD

View full text Add to dashboard Cite

Introduction: Exposure to the low frequency electric and magnetic fields (ELF-EMF) is very common in workers occupied in the combined cycle power plant during work shifts The present study aimed to measure ELF-EMF flux density among shift and non-shift workers, determine job stress among workers and office workers, and identify major factors associated with job stress in the studied groups. Materials and Methods: In this cross-sectional study, the exposed group was divided into 75 shift workers and 75 non-shift workers. Seventy-five office workers were selected as the reference group. The participants’ exposure to ELF-EMF was measured by the EMF-828 device. In addition, Osipow Occupational Stress Questionnaire was used to assess the participants’ stress levels. Results: Maximum levels of ELF-EMF among shift workers, non-shift workers, and office workers were 28.67 μT, 23.43 μT, and 0.06 μT, respectively. Although the explosion rate to ELF-EMF was higher in the shift and non-shift workers than the office one's, this rate in both of them were lower than the recommended limit as suggested by the American Conference of Governmental Industrial Hygienists (ACGIH). The highest stress score was related to shift workers exposed to ELF-EMF, in which 42.7% of them experienced moderate to high levels of job stress. Multivariate linear regression analysis showed a significant association between shift work and exposure to ELF-EMF with increased stress. Conclusion: The findings suggested that exposure to ELF-EMF, even at low intensities, is associated with increased stress. Moreover, Shift work is another risk factor for stress.

show abstract

Investigating the effects of exposure to extremely low frequency electromagnetic fields on job burnout syndrome and the severity of depression; the role of oxidative stress

Cited by 13 publications

References 47 publications

Maternal stress induced anxiety-like behavior exacerbated by electromagnetic fields radiation in female rats offspring

Maternal stress induced anxiety-like behavior exacerbated by electromagnetic fields radiation in female rats offspring

Impressions of the chronic 900-MHz electromagnetic field in the prenatal period on Purkinje cells in male rat pup cerebella: is it worth mentioning?

Job Stress among Workers Exposed to Extremely Low Frequency Electric and Magnetic Fields in a Combined Cycle Power Plant

Contact Info

Product

Resources

About