Investigating the Involvement of Cytokines and Neurotrophic Factors in the Advanced Stages of Huntington’s Disease: A BACHD Study

Valadão, Priscila Aparecida Costa; Oliveira, Bruna da Silva; Machado, Caroline Amaral; Fernandes, Heliana de Barros; Machado, Thatiane Cristina; Soares, Kívia Santos; Teixeira, Antônio Lúcio; Guatimosim, Cristina; Miranda, Aline Silva de

doi:10.26420/austinalzheimersjparkinsonsdis.2023.1034

austinalzheimersjparkinsonsdis

2023

DOI: 10.26420/austinalzheimersjparkinsonsdis.2023.1034

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Investigating the Involvement of Cytokines and Neurotrophic Factors in the Advanced Stages of Huntington’s Disease: A BACHD Study

Priscila Aparecida Costa Valadão¹,

Bruna da Silva Oliveira²,

Caroline Amaral Machado³

et al.

Abstract: Neuroinflammation seems to be involved in the pathophysiology of Huntington’s Disease (HD), but its specific role on different stages of the disease, especially in later stages, remains to be understood. Here in, we investigated the concentrations of cytokines, chemokines and neurotrophic factors in striatum and frontal cortex of 24-month-old BACHD mice, a murine model of that displays several behavioral and pathological features of human HD. Our results revealed increased concentrations of the chemokine MCP-1… Show more

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Cited by 5 publications

References 32 publications

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Standards, territory and frontier: environmental policy and the expansion of mining in Minas Gerais

Magno,

Gouvêa,

Oliveira

et al. 2024

Rev. Bras. Estud. Urbanos Reg.

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This article aims to debate the environmental policy in the state of Minas Gerais based on observing the standards adopted and the territorial reflexes, highlighting how the relaxing the environmental licensing processes over the past few years has influenced the expansion of the frontier of mining activities to different mesoregions of Minas Gerais. Based on a literature review, documentary research and data available in the System for Consultations and Decisions on Environmental Licensing Processes from the State Secretariat for the Environment and Sustainable Development (SEMAD) and in the Spatial Data Infrastructure (IDE) of the State Environmental System (SISEMA) The text initially characterizes the institutionalization of environmental policy in Minas Gerais, and then analyzes the recent changes in the state’s environmental licensing. Lastly, the territorial implications are indicated by the advance of the frontier of the mineral sector and the corporate mining territories. The analyzes on the changes in licensing and the expansion of the mineral sector in the state cover the period between 2013 and 2022.

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Standards, territory and frontier: environmental policy and the expansion of mining in Minas Gerais

Magno,

Gouvêa,

Oliveira

et al. 2024

Rev. Bras. Estud. Urbanos Reg.

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Association between body dissatisfaction and eating disorder symptomatology in professional dancers

Reis,

Alencar,

Borgatto

et al. 2024

Journal of Sport Pedagogy &Amp; Research

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The aim was to investigate the association between body image dissatisfaction and eating disorder symptomatology in professional dancers in Brazil. A total of 127 dancers of classical ballet or contemporary dance modalities from professional companies in Brazil participated. Data were collected through a self-administered online questionnaire. Multiple logistic regression showed that dancers with anorexia nervosa symptomatology had 1.13 more odds of being dissatisfied with overweight and dancers with bulimia nervosa symptomatology had 1.28 more odds of being dissatisfied with thinness, in both cases demonstrating a desire for an extremely rigid ideal of thinness. Higher scores of eating disorder symptomatology are associated with greater odds of body image dissatisfaction in Brazilian professional dancers of classical and contemporary companies.

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Gestão sustentável do saneamento Nota Técnica 4 – A aplicação da avaliação do ciclo de vida em diferentes níveis de tratamento de esgoto

Gutierrez,

Fernandes,

Chernicharo

2022

Cad. Téc. Eng. Sanit. Ambiente.

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A avaliação de ciclo de vida (ACV) vem sendo adotada como importante instrumento de apoio aos tomadores de decisão do setor de saneamento, em especial em questões relacionadas ao tratamento de esgoto sanitário e a destinação de seus subprodutos. Esse trabalho busca apresentar a versatilidade dessa ferramenta, trazendo exemplos de aplicação da metodologia em diferentes cenários. Apresentamos um estudo simulado, para atendimento a pequenas populações, que compara dois sistemas combinados anaeróbio e aeróbio na destinação do lodo e biogás produzido e que traz como principal ponto crítico a potencialidade de impacto relacionada à cal comumente utilizada na desinfecção de lodo de esgoto, quando do seu uso como biossólido. No estudo de caso de uma estação de tratamento de esgoto (ETE) do tipo lodos ativados convencional, mesmo com a adoção de um sistema de aquecimento dos biodigestores de lodo e aproveitamento da energia elétrica na própria ETE, proporcionados pela instalação de um sistema de cogeração de energia, parte importante da energia térmica produzida é desperdiçada. Esse resultado aponta a necessidade de aprimoramento das rotas de destinação dessa energia para melhora do desempenho ambiental global da ETE e amplia a discussão sobre possíveis usos da energia térmica, como, por exemplo, a secagem do lodo com fins de desinfecção para uso como biossólido ou apenas para redução de volume de lodo transportado a aterros sanitários. No terceiro trabalho, para atendimento ao enquadramento do curso d’agua receptor, já que a ETE se encontra instalada no centro do município e causa importante impacto na qualidade de vida dos moradores do entorno, foram propostas alternativas

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Investigating the Involvement of Cytokines and Neurotrophic Factors in the Advanced Stages of Huntington’s Disease: A BACHD Study

Cited by 5 publications

References 32 publications

Standards, territory and frontier: environmental policy and the expansion of mining in Minas Gerais

Standards, territory and frontier: environmental policy and the expansion of mining in Minas Gerais

Association between body dissatisfaction and eating disorder symptomatology in professional dancers

Gestão sustentável do saneamento Nota Técnica 4 – A aplicação da avaliação do ciclo de vida em diferentes níveis de tratamento de esgoto

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