2024
DOI: 10.1002/jbt.23747
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Investigating the role of rotenone on human blood platelets: Molecular insights into abnormal platelet functions in Parkinson's disease

Samir Kumar Beura,
Gaurahari Sahoo,
Sonika Yadav
et al.

Abstract: Parkinson's disease (PD) is a predominant neuromotor disorder characterized by the selective death of dopaminergic neurons in the midbrain. The majority of PD cases are sporadic or idiopathic, with environmental toxins and pollutants potentially contributing to its development or exacerbation. However, clinical PD patients are often associated with a reduced stroke frequency, where circulating blood platelets are indispensable. Although platelet structural impairment is evident in PD, the platelet functional a… Show more

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