Investigation and management of canine osteoarthritis

Pettitt, Rob; German, Alexander J.

doi:10.1136/inp.h5763

Cited by 55 publications

(61 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Veterinary examination can reveal and detect aspects of joint disease that are not appreciable to untrained owners and it may be unfair to assume that all elbow joint cases should be easily recognisable to owners. Typical clinical signs indicative of advanced joint remodelling associated with osteoarthritis were identified on veterinary examination have been reported in 1/5 (thickening) to 1/4 (crepitus) dogs, and 50% of diagnoses were made on clinical examination [61].…”

Section: Discussionmentioning

confidence: 97%

Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK

O’Neill

Brodbelt

Hodge

et al. 2020

Canine Genet Epidemiol

View full text Add to dashboard Cite

Background: Conditions affecting the elbow joint are a common cause of lameness in dogs. Primary-care veterinary clinical data are now recognised as a valuable research resource. Using data from the VetCompass Programme, this study aimed to report the frequency and risk factors for elbow joint disease in dogs under primary veterinary care in the UK and describe clinical management. Results: From 455,069 dogs under veterinary care, the one-year period prevalence for elbow joint disease diagnosis was 0.56% (95% CI: 0.53-0.60). Of 616 incident cases, the most common specific variants of elbow joint disease were osteoarthritis (n = 468, 75.97%), elbow dysplasia (190, 30.84%) and traumatic (41, 6.66%). The most common signs described by the owners were lameness (n = 466, 75.65%), difficulty exercising (123, 19.97%) and pain (86, 13.96%). The most common findings recorded on veterinary examination were pain (n = 283, 45.94%), lameness (278, 45.13%) and reduced range of movement (243, 39.45%). Common medications used included non-steroidal anti-inflammatory drugs (n = 544, 88.31%), tramadol (121, 19.64%) and disease modifying agents (118, 19.16%). Of 109 deaths involving euthanasia with information available from the 616 incident cases, elbow joint disease contributed to the decision to euthanase in 45 (41.28%) dogs. Five breeds showed increased odds of elbow joint disease compared with crossbred dogs: Rottweiler (OR: 6.16, 95% CI 3.89-9.75), Labrador Retriever (OR: 5.94, 95% CI 4.65-7.60), German Shepherd Dog (OR: 4.13, 95% CI 2.88-5.93), Golden Retriever (OR: 3.11, 95% CI 1.93-5.00) and English Springer Spaniel (OR: 2.00, 95% CI 1.26-3.18). Additional risk factors included having an adult bodyweight that was equal or higher than their breed/sex mean, advancing age, being male, being neutered, being insured and larger bodyweight. Conclusions: Elbow joint disease is a relatively common diagnosis in dogs and has a high welfare impact as evidenced by the high proportion of cases recorded with pain, lameness and analgesic therapy. There are strong breed predispositions, in particular for large breed dogs. These findings present a clear case for improved breeding programmes to reduce the burden of elbow joint disease.

show abstract

Section: Discussionmentioning

confidence: 97%

Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK

O’Neill

Brodbelt

Hodge

et al. 2020

Canine Genet Epidemiol

View full text Add to dashboard Cite

show abstract

“…Among the musculoskeletal disorders group, the most common fine level disorder was degenerative joint disease which was recorded in 4.69% of Rottweilers. The main clinical presenting signs of degenerative joint disease are lameness, stiffness, exercise intolerance and/or an unwillingness/inability to climb or jump [ 94 ] which suggests that this condition impacts substantially on welfare and lifestyle. The UK KC currently recommends that scores from the BVA/KC Hip Dysplasia Scheme and BVA/KC Elbow Dysplasia Scheme contribute to breeding decisions for Rottweilers but it may worth also considering other functional joint testing in addition as part of this process [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

Rottweilers under primary veterinary care in the UK: demography, mortality and disorders

O’Neill

Seah

Church

et al. 2017

Canine Genet Epidemiol

View full text Add to dashboard Cite

BackgroundRottweilers are reportedly predisposed to many disorders but accurate prevalence information relating to the general population are lacking. This study aimed to describe demography, mortality and commonly recorded diseases in Rottweilers under UK veterinary care. Clinical health records within the VetCompass Programme were explored for disorders recorded during 2013.ResultsRottweilers comprised 5321 (1.17%) of 455,557 dogs attending 304 clinics. Annual proportional birth rates dropped from 1.75% in 2006 to 1.07% in 2013. Median adult bodyweight overall was 44.9 kg (IQR 39.55–51.00, range 20.00–88.80). Median male adult bodyweight (48.5 kg, interquartile range [IQR] 43.0–54.0, range 20.0–88.8) was heavier than female (41.5 kg, IQR 37.0–46.4, range 21.1–73.5) (P < 0.001). Median longevity overall was 9.0 years (IQR 7.2–10.5, range 0.0–17.0). Median female longevity (9.5 years, IQR 7.8–11.0) was greater than male (8.7 years, IQR 6.8–10.1) (P = 0.002). The most common causes of death were neoplasia (33.0%), inability to stand (16.0%) and mass-associated disorder (7.1%).At least one disorder was recorded for 60.31% of Rottweilers. The most prevalent specific disorders recorded were aggression (7.46%, 95% CI 6.40–8.64), overweight/obesity (7.06%, 95% CI: 6.02–8.21), otitis externa (6.14%, 95% CI: 5.18–7.23) and degenerative joint disease (4.69%, 95% CI: 3.84–5.66). Male Rottweilers had higher prevalence than females for aggression (9.36% versus 5.47%, P = 0.001) and pyotraumatic dermatitis (4.05% versus 1.76%, P = 0.001). Aggression was more prevalent in neutered than entire females (7.5% versus 3.1%, P = 0.003) but did not differ between neutered and entire males (9.6% versus 9.0%, P = 0.773). The most frequent disorder groups were musculoskeletal (12.01%, 95% CI: 10.69–13.45), dermatological (10.96%, 95% CI: 9.69–12.35), gastro-intestinal (195, 8.87%, 95% CI: 7.72–10.14), undesirable behaviour (7.96%, 95% CI: 6.87–9.18) and neoplasia (7.96%, 95% CI: 6.87–9.18).ConclusionsThe current study assists prioritisation of health issues within Rottweilers. Rottweilers are relatively short-lived and neoplasia is a common cause of death. The most common disorders were aggression, overweight/obesity, otitis externa and degenerative joint disease. Males were significantly heavier, shorter-lived and predisposed to aggression than females. These results can alert prospective owners to potential health issues and optimise sex selection decision-making.

show abstract

“…The duration that dogs are affected by OA has not been well informed in the literature due to difficulty in identifying the exact onset of the disorder and limited accessibility of long-term cohort clinical data on confirmed cases. Even though the OA may initiate at any age, it may not be clinically diagnosed until it reaches an advanced stage with clear external clinical symptoms [89]. Moreover, even though joint deterioration may already be existing when the originating cause is identified, at this point, it may not have been recorded or encoded as OA in clinical notes yet.…”

Section: Oa Prevalence In Dogsmentioning

confidence: 99%

“…Predictions from North America have reported that the age-specific OA prevalence ranged from 20 percent in dogs older than 1 year to 80 percent in dogs older than 8 years, depending on radiographic and clinical data [91], whereas dog OA prevalence in the reported literature shows contradictory values. In the UK dog population, estimations have ranged from 6.6 percent based on primary-care data [9] to 20 percent based on referral data [89]. In the UK, among 16,437 identified candidate OA cases, 6104 of them were checked manually and 4196 of the dogs (69%) were confirmed as cases.…”

Section: Oa Prevalence In Dogsmentioning

confidence: 99%

Undenatured Type II Collagen (UC-II) in Joint Health and Disease: A Review on the Current Knowledge of Companion Animals

Gençoğlu

Orhan

Şahin

et al. 2020

Animals

View full text Add to dashboard Cite

OA is quite common in companion animals, especially in large breed dogs and horses. Collagen, the most abundant protein of mammals, has specific connective tissue types for skin, bones, reticulate, basal lamina, bones, cell surfaces, while type II collagen (UC-II) forms the main structure of cartilage tissue. Even at the smaller dosages, UC-II has also been reported to be more effective than the glucosamine and chondroitin sulfate supplements, which are the supplements most frequently used in the market. In this review, we summarize the effects of UC-II on joint health and function in health and disease conditions in companion animals.

show abstract

Investigation and management of canine osteoarthritis

Cited by 55 publications

References 25 publications

Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK

Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK

Rottweilers under primary veterinary care in the UK: demography, mortality and disorders

Undenatured Type II Collagen (UC-II) in Joint Health and Disease: A Review on the Current Knowledge of Companion Animals

Contact Info

Product

Resources

About