Investigation of a Candida auris outbreak in a skilled nursing facility — Virginia, United States, October 2020–June 2021

Waters, Ansley; Chommanard, Christina; Baltozer, Sara; Angel, Luisa Cortes; Abdelfattah, Rehab; Lyman, Meghan; Forsberg, Kaitlin; Misas, Elizabeth; Litvintseva, Anastasia P.; Fields, Virgie; Lineberger, Sarah; Bernard, Shaina

doi:10.1016/j.ajic.2022.12.003

Cited by 8 publications

(7 citation statements)

References 7 publications

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“…Practice issue-nonadherence with the manufacturer's instructions for use (IFU) and procedure 31 Appropriate disinfectant for environmental surface but not used per IFU, such as incorrect contact time…”

Section: Infection Prevention Issue Detailmentioning

confidence: 99%

“…Practice breaches-inconsistent adherence with infection prevention and control (IPC) measures 31 Failure to implement contact precautions Failure to perform hand hygiene (despite available hand sanitizer)…”

Section: Infection Prevention Issue Detailmentioning

confidence: 99%

“…[27][28][29] Failure to perform hand hygiene, use personal protective equipment and precautions, and a lack of or inadequate cleaning and disinfection of equipment and environmental surfaces can facilitate spread (see Transmission examples). [30][31][32] IPC recommendations 26…”

Section: Failure To Use Personal Protective Equipmentmentioning

confidence: 99%

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Candida auris

Borton

2024

Nursing

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Section: Infection Prevention Issue Detailmentioning

confidence: 99%

Section: Infection Prevention Issue Detailmentioning

confidence: 99%

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Candida auris

Borton

2024

Nursing

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“…and include prolonged time of hospital stay, indwelling central venous access devices (CVADs) and urinary catheters, and high-acuity care requirement, mechanical ventilation in particular [144,152,153]. It seems particularly suited to the intensive care unit (ICU) environment and ventilator units [92,154] and has shut down entire ICU wards due to transmission [92]. The duration of colonization with C. auris remains unclear; one study revealed a median duration of 8.6 months [155], but more work is needed in this area, particularly as screening is not 100% sensitive, with the tendency to repeatedly detect C. auris on subsequent testing despite a single negative intervening result [151].…”

Section: Candida Aurismentioning

confidence: 99%

Outbreaks of Fungal Infections in Hospitals: Epidemiology, Detection, and Management

Douglas,

Stewart,

Halliday

et al. 2023

JoF

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Nosocomial clusters of fungal infections, whilst uncommon, cannot be predicted and are associated with significant morbidity and mortality. Here, we review reports of nosocomial outbreaks of invasive fungal disease to glean insight into their epidemiology, risks for infection, methods employed in outbreak detection including genomic testing to confirm the outbreak, and approaches to clinical and infection control management. Both yeasts and filamentous fungi cause outbreaks, with each having general and specific risks. The early detection and confirmation of the outbreak are essential for diagnosis, treatment of affected patients, and termination of the outbreak. Environmental sampling, including the air in mould outbreaks, for the pathogen may be indicated. The genetic analysis of epidemiologically linked isolates is strongly recommended through a sufficiently discriminatory approach such as whole genome sequencing or a method that is acceptably discriminatory for that pathogen. An analysis of both linked isolates and epidemiologically unrelated strains is required to enable genetic similarity comparisons. The management of the outbreak encompasses input from a multi-disciplinary team with epidemiological investigation and infection control measures, including screening for additional cases, patient cohorting, and strict hygiene and cleaning procedures. Automated methods for fungal infection surveillance would greatly aid earlier outbreak detection and should be a focus of research.

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“…Candida auris is an emerging and often multidrug-resistant fungal pathogen that persistently colonizes patients and spreads in healthcare settings. [1][2][3][4] Studies have described duration of C. auris colonization in postacute care facilities (PACFs) and outside healthcare settings. 5,6 However, few data are available regarding its persistence among hospitalized patients, in whom colonization can increase the risk for developing C. auris candidemia.…”

mentioning

confidence: 99%