Investigation of activation cross-sections of proton induced nuclear reactions on natMo up to 40MeV: New data and evaluation

Tárkányi, F.; Ditrói, F.; Hermanne, Alex; Takács, S.; Ignatyuk, A. V.

doi:10.1016/j.nimb.2012.02.029

Cited by 57 publications

(36 citation statements)

References 38 publications

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“…Several measurements have been reported in recent years [32][33][34][35][36] and the data show large scatter, especially over the energy range of 10-20 MeV. Nuclear model calculations show [37] that the more recent data [33][34][35][36] are consistent. An evaluation has produced a recommended set of cross sections [37], which should allow calculation of the yield with enhanced confidence.…”

Section: Several Routes Have Been Suggested and Their Cross Sections mentioning

confidence: 88%

New trends in nuclear data research for medical radionuclide production

Qaim

2013

Radiochimca Acta

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Medical radionuclide / Optimisation of production route / Nuclear reaction cross section / Standardisation of data / Alternative routes for production of 99m Tc and 68 Ga / Non-standard positron emitter / Novel therapeutic radionuclide Summary. Nuclear reaction cross section data are of great significance in optimisation of production routes of radionuclides. This article deals with some newer aspects of data research related to production of both standard and novel radionuclides. The recent work to standardise the known data is discussed and new measurements with regard to further optimisation of production routes of some commonly used radionuclides are mentioned. Attempts to increase the specific activity of some reactor-produced radionuclides through the use of charged-particle induced reactions are outlined. The jeopardy in the supply of 99m Tc via a fission-produced 99 Mo/ 99m Tc generator is considered and its possible direct production at a cyclotron is briefly discussed. Regarding the novel radionuclides, development work is presently focussed on non-standard positron emitters for diagnosis and on low-range highly ionising radiation emitters for internal radiotherapy. Recent nuclear reaction cross section measurements related to the production of the two types of radionuclides are briefly reviewed and some anticipated trends in nuclear data research are considered.

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Section: Several Routes Have Been Suggested and Their Cross Sections mentioning

confidence: 88%

New trends in nuclear data research for medical radionuclide production

Qaim

2013

Radiochimca Acta

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“…Although subsequent measurements and evaluations [cf . [103][104][105][106] showed slightly higher cross sections, the basic conclusion given in [102] did not change. The 100 Mo(d, t + p2n) 99 Mo reaction has a threshold of about 20 MeV and the cross section is lower than for the proton induced reaction [cf .…”

Section: Mo and 99m Tcmentioning

confidence: 90%

The present and future of medical radionuclide production

Qaim

2012

Radiochimica Acta

103

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Reactor and cyclotron production of medical radionuclides / γ -ray emitters for SPECT / Positron emitters for PET / Corpuscular radiation emitters for internal radiotherapy / Low and intermediate energy nuclear reactions / Radionuclide generators / Future directionsSummary. Medical radionuclide production technology is well established. Both reactors and cyclotrons are utilized for production; the positron emitters, however, are produced exclusively using cyclotrons. A brief survey of the production methods of most commonly used diagnostic and therapeutic radionuclides is given. The emerging radionuclides are considered in more detail. They comprise novel positron emitters and therapeutic radionuclides emitting low-range electrons and α-particles. The possible alternative production routes of a few established radionuclides, like 68 Ga and 99m Tc, are discussed. The status of standardisation of production data of the commonly used as well as of some emerging radionuclides is briefly mentioned. Some notions on anticipated future trends in the production and application of radionuclides are considered.

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“…Several attempts have been made to elaborate methods to substitute the reactor HEU (highly enriched uranium) production route by LEU (low enriched uranium target), fast neutron [15,16], high energy photon [17] and charged particle irradiation, both for 99 Mo production [18,19] and direct 99m Tc production [20]. Fig.…”

Section: Production Ofmentioning

confidence: 99%

“…The emitted α-particles are relatively heavy projectiles, having different energies with short range in human tissues. Thats why they can easily induce the medically required double-strand DNA break in the tumor cells without damaging the 99 Mo production by charged particle activation on natural Mo [6,7,18,19] and 100 Mo enriched targets [20] surrounding healthy cells. New results have been published for the α-particle and proton induced production of 211 At [22] and 225 Ac [23,24] respectively.…”

Section: Heavy α-Emittersmentioning

confidence: 99%

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New developments in the experimental data for charged particle production of medical radioisotopes

Ditrói

Tárkányi

Takács

et al. 2015

J Radioanal Nucl Chem

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The goal of the present work is to give a review of developments achieved experimentally in the field of nuclear data for medically important radioisotopes in the last three years. The availability and precision of production related nuclear data is continuously improved mainly experimentally. This review emphasizes a couple of larger fields: the Mo/Tc generator problem and the generator isotopes in general, heavy alpha-emitters and the rare-earth elements. Other results in the field of medical radioisotope production are also listed.

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Investigation of activation cross-sections of proton induced nuclear reactions on natMo up to 40MeV: New data and evaluation

Cited by 57 publications

References 38 publications

New trends in nuclear data research for medical radionuclide production

New trends in nuclear data research for medical radionuclide production

The present and future of medical radionuclide production

New developments in the experimental data for charged particle production of medical radioisotopes

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