Investigation of acupoint specificity by functional connectivity analysis based on graph theory

Ren, Yanshuang; Bai, Lijun; Feng, Yanghe; Tian, Jie

doi:10.1016/j.neulet.2010.06.091

Cited by 36 publications

(28 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, in the contralateral side, the blood increase in an acupoint after stimulation may be independent of the adenosine receptor activation. It has been shown that acupuncture at different acupoints exhibited differential hemodynamic neural responses in some brain areas, 23 and these specific acupuncture-associated modulatory effects could be sustained during the stimulation phase, and even remained in the subsequent resting epoch. Signal changes in some brain regions during the postrest epoch of the acupuncture were even higher than that of the stimulation epoch.…”

Section: Discussionmentioning

confidence: 99%

Change of Blood Perfusion in Hegu Acupoint After Contralateral Hegu Acupoint Was Stimulated

Wang

Tian

Jia

et al. 2012

The Journal of Alternative and Complementary Medicine

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Change of Blood Perfusion in Hegu Acupoint After Contralateral Hegu Acupoint Was Stimulated

Wang

Tian

Jia

et al. 2012

The Journal of Alternative and Complementary Medicine

View full text Add to dashboard Cite

show abstract

“…According to the Huang Di Nei Jing Su Wen [2], acupoint specificity is an essential principle [3,4], which means that the therapeutic efficacy mainly results from the correct acupoint choice and acupuncture effects are absolutely related to the appropriate acupoint selection during the treatment. Although many researchers believe that a placebo effect is the best explanation for acupuncture [5], acupoint specificity was strengthened by evidence from both clinical practice [6,7] and basic exploration [8]. …”

Section: Introductionmentioning

confidence: 99%

Acupuncture Point Laterality: Evidence and Perspective

Wang

Litscher²,

Tian

et al. 2014

Integr Med Int

View full text Add to dashboard Cite

Background: In the Yellow Emperor Neijing, it is stated that ‘if someone has a disease related with the left side, the treatment point is on the right side, and vice versa' [Unschuld PU: Huang Di Nei Jing Su Wen, 2003], which emphasizes that specific lateral-side acupoint stimulation might lead to therapeutic advantages under specific conditions. Methods: We summarize the different effects resulting from namesake acupoint stimulation referred to as acupoint laterality. In this short review, the evidence of acupoint lateralization from Neiguan (PC6), Hegu (LI4), and Quchi (LI11) is discussed. Results and Conclusion: Investigations indicate that acupuncture at the contralateral side of PC6 has different effects on heart rate variability (HRV), which means that PC6 has laterality. However, such a difference in HRV could not be observed when the same stimulation was applied to both sides of LI4, although the difference in blood perfusion distribution was confirmed exactly. Considering the results from PC6, we hypothesize that acupoint laterality might be related to acupoint specificity. Although the evidence is not clear, our results indicate that in patients with hypertension, different-side LI11 stimulation can also produce different results, which might indicate that acupoint laterality is associated with the functional state of subjects. The perspective of acupoint lateralization is also preliminarily discussed in this review. i 2014 S. Karger AG, Basel

show abstract

“…Acupoint specificity is often considered as the foundation of the theory and treatment of acupuncture (57). Evidence derived from brain imaging and biological studies demonstrated that the point specificity does exist (58)(59)(60)(61).…”

Section: Principal Features Of Acupuncture Intervention Efficacymentioning

confidence: 99%

Is acupuncture no more than a placebo? Extensive discussion required about possible bias

Deng

Zhao

et al. 2015

Experimental and Therapeutic Medicine

View full text Add to dashboard Cite

Abstract. Numerous randomized controlled trials (RCTs) of acupuncture have been conducted in recent years. The results of several studies implied that acupuncture was only a powerful placebo; however, certain studies demonstrated that verum acupuncture had a greater effect than placebo and the mechanisms between a verum acupuncture group and a placebo/sham group were different. Researchers attempted to investigate the inherent factors that may potentially influence the results of trials. Certain problems observed in acupuncture RCTs also occurred in RCTs in other fields, including insufficient sample size, high dropout rates, inadequate follow-up and randomization. The study of acupuncture is so complex that specific methodological challenges are raised, which are frequently overlooked, including sham interventions, blinding, powerful placebo effects (even stronger than an inert pill) and variations in acupuncture administration. The aforementioned problems may contribute to bias, and researchers systematically attempt to solve these problems. The present review aimed to suggest techniques to design high-quality studies, minimize the placebo effect and optimize acupuncture administration in acupuncture studies. If these problems are addressed, then the results of acupuncture studies may be different.

show abstract

Investigation of acupoint specificity by functional connectivity analysis based on graph theory

Cited by 36 publications

References 21 publications

Change of Blood Perfusion in Hegu Acupoint After Contralateral Hegu Acupoint Was Stimulated

Change of Blood Perfusion in Hegu Acupoint After Contralateral Hegu Acupoint Was Stimulated

Acupuncture Point Laterality: Evidence and Perspective

Is acupuncture no more than a placebo? Extensive discussion required about possible bias

Contact Info

Product

Resources

About