Investigation of an improved MAA-based polymer gel for thermal neutron dosimetry

Abtahi, Seyed Mohammad Mahdi; Zahmatkesh, Mohammad Hasan; Khalafi, H.

doi:10.1007/s10967-015-4469-7

Cited by 25 publications

(7 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 21,80 ] In turn, the addition of agarose to gelatine in MAGIC increased the melting point to 60 °C and eliminated the use of formaldehyde (MAGIC‐A). [ 81 ] The poly(vinyl alcohol) matrix used in the PAGAT dosimeter increased the melting point to 80 °C (PVABAT). [ 82 ]…”

Section: Introductionmentioning

confidence: 99%

First Combined, Double‐Density LCV‐Pluronic F‐127 Radiochromic Dosimeter Mimicking Lungs and Muscles

Kozicki

Bartosiak

Maras

et al. 2023

Adv Materials Technologies

View full text Add to dashboard Cite

3D chemical dosimetry of radiotherapy is an interdisciplinary research related to medical physics, polymer and radiation chemistry, photochemistry, organic chemistry, computer science, oncology, materials engineering, and automation technology. It consists of a 3D high resolution tissue equivalent dosimeter, high resolution 3D reading, and software packages for fast processing of 3D measurement data. Research on 3D radiotherapy chemical dosimetry has been going on for almost forty years, starting with the first proposal of a 3D dosimeter -Fricke dosimetric solution in a physical gel matrix with magnetic resonance imaging (MRI) reading to record the spatial dose distribution. [1] Further research concerned both Fricke-gel dosimeters and other systems, such as polymer gel dosimeters, radiochromic gel and plastic dosimeters, and flexible dosimeters. Many dosimetric compositions have been proposed. As a general rule, each new 3D dosimeter has a specific acronym, usually derived from its components. Examples of 3D polymer gel dosimeters are as follows (the acronyms are associated with example references): BANG, [16] PAG, [17] PAGAT, [18] nMAG, nPAG, [19] MAGIC, [17,20] MAGIC-f, [21] NIPAM, [22,23] VIPAR, [24] VIP (VIPAR nd ), [25] VIC, [26] VIC-T, [26] VIP3-Pluronic F-127, [27,28] PAGAT2-Pluronic F-127, [29] PAB-IG nx , [14,30,31] NHMAGAT, [32] MAGADIT, [33] NMPAGAT. [34] Examples of 3D radiochromic dosimeters are as follows: PVA-GTA-XO-Fricke, [35,36] PVA-GTA-MTB-Fricke, [37] Fricke-XOgelatine, [38] Fricke-XO-Pluronic F-127, [10,13,39] TTC-Pluronic F-127, [40] NBT-Pluronic F-127, [41,42] KI-PVA, [43] KI-Pluronic F-127, [12] LCV-gelatine; [44] and 3D plastic radiochromic dosimeter: PRESAGE. [3,45,46] 3D flexible dosimeters have also been proposed: LMG-silicone, [47,48] FlexyDos3D, [49] as well as 3D lung-mimicking dosimeters: PAGAT-2-Pluronic F-127 foam, [11] foam based on methacrylic acid-gelatine infused with sodium dodecyl sulphate surfactant, [50] and methacrylic acid-gelatine gel with expanded polystyrene spheres. [51] It should be mentioned that alternative 3D reading techniques to MRI were also investigated, including computed tomography (CT), [22,23,52] ultrasonography, [53][54][55] and optical computed tomography (optical CT). [56,57] It has been shown that 3D dosimetry data This work reports on a new type of combined radiochromic ionizing radiation dosimeter for radiotherapy. The LCV-Pluronic F-127 serves for this purpose, which is a leuco crystal violet embedded in a physical hydrogel matrix of poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F-127) with additives. This dosimeter responds to ionizing radiation by developing a blue color with an intensity related to the radiation dose. The LCV-Pluronic F-127 dosimeter is improved for lower temperature stability by adding sodium chloride (NaCl). Subsequently, a method for manufacturing the LCV-Pluronic F-127 lung mimicking dosimeter is proposed. Next, the LCV-Pluronic F-127 3D composite dosimeter is elaborated, which cont...

show abstract

Section: Introductionmentioning

confidence: 99%

First Combined, Double‐Density LCV‐Pluronic F‐127 Radiochromic Dosimeter Mimicking Lungs and Muscles

Kozicki

Bartosiak

Maras

et al. 2023

Adv Materials Technologies

View full text Add to dashboard Cite

show abstract

“…In 1958, monomer polymerisation was established as a dosimetry process whereby polymerisation occurs upon irradiation [ 42 ]. Notably, the gel dosimeter exhibits outstanding performance in measuring sophisticated 3D dose distribution, and it possesses tissue equivalency, strong spatial resolution, independence of radiation direction, and dose integration capability during the treatment [ 43 , 44 ].…”

Section: Introductionmentioning

confidence: 99%

A Review of PRESAGE Radiochromic Polymer and the Compositions for Application in Radiotherapy Dosimetry

et al. 2022

View full text Add to dashboard Cite

Recent advances in radiotherapy technology and techniques have allowed a highly conformal radiation to be delivered to the tumour target inside the body for cancer treatment. A three-dimensional (3D) dosimetry system is required to verify the accuracy of the complex treatment delivery. A 3D dosimeter based on the radiochromic response of a polymer towards ionising radiation has been introduced as the PRESAGE dosimeter. The polyurethane dosimeter matrix is combined with a leuco-dye and a free radical initiator, whose colour changes in proportion to the radiation dose. In the previous decade, PRESAGE gained improvement and enhancement as a 3D dosimeter. Notably, PRESAGE overcomes the limitations of its predecessors, the Fricke gel and the polymer gel dosimeters, which are challenging to fabricate and read out, sensitive to oxygen, and sensitive to diffusion. This article aims to review the characteristics of the radiochromic dosimeter and its clinical applications. The formulation of PRESAGE shows a delicate balance between the number of radical initiators, metal compounds, and catalysts to achieve stability, optimal sensitivity, and water equivalency. The applications of PRESAGE in advanced radiotherapy treatment verifications are also discussed.

show abstract

“…When used as a cross-linking agent, its residual concentration contributes to the toxicity of the gel dosimeter. Another attempt was to add 0.5 % w / w agarose to the gelatin matrix [ 22 ], which increased the sol-gel stability to about 60 °C, but the sensitivity of the dosimeter decreased significantly. In turn, it should be emphasized that the Fricke-based 3D gel dosimeters may be not stable at elevated temperatures.…”

Section: Introductionmentioning

confidence: 99%

Impact of Salt on Thermal Stability and Dose Response of the Fricke-XO-Pluronic F-127 3D Radiotherapy Dosimeter

et al. 2022

View full text Add to dashboard Cite

Fricke-XO-Pluronic F-127 has recently been proposed as a 3D dosimeter for radiotherapy. It contains the typical ingredients of the Fricke ionizing radiation dosimeter, which are embedded in a physical gel of poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic F-127). The main reactions upon irradiation are the conversion of Fe+2 to Fe+3 and the formation of a colored complex with XO ([XO-Fe]+3). The study attempts to optimize the dosimeter in terms of its solution-to-gel transition temperature. In order to lower this temperature, the use of NaCl salt has been proposed. The new composition was characterized in order to obtain information on its thermal performance, storage stability, dose response to irradiation with a medical accelerator emitting different types of radiation, and tissue equivalence. The results obtained show an improvement in the sol-gel transition temperature and dose sensitivity compared to the composition without NaCl and broaden the knowledge of the Fricke-XO-Pluronic F-127.

show abstract

Investigation of an improved MAA-based polymer gel for thermal neutron dosimetry

Cited by 25 publications

References 45 publications

First Combined, Double‐Density LCV‐Pluronic F‐127 Radiochromic Dosimeter Mimicking Lungs and Muscles

First Combined, Double‐Density LCV‐Pluronic F‐127 Radiochromic Dosimeter Mimicking Lungs and Muscles

A Review of PRESAGE Radiochromic Polymer and the Compositions for Application in Radiotherapy Dosimetry

Impact of Salt on Thermal Stability and Dose Response of the Fricke-XO-Pluronic F-127 3D Radiotherapy Dosimeter

Contact Info

Product

Resources

About