Investigation of analgesic activity of Ptersospermum canescens, Roxb., (Sterculiaceae) extracts in experimental animals

Abstract

Pain is an perception alone which does not require cortex. A lot of research is going on worldwide towards finding analgesic agents from the natural sources. The main aim of the present study was to investigate analgesic activity of petroleum ether, chloroform and methanol extracts (100 mg/kg, 200 mg/kg) of Pterospermum canescens, Roxb., (Sterculiaceae-leaf, stem and stem bark) andwas carried out by eddy's hot plate method using Indomethacin as standard (10 µg/kg). This present investigation revealsthat the methanol leaf and stem bark extracts were exhibited significant (P < 0.05) increase in animal reaction time to heat stimulus that at 200 mg/kg in experimental animals.