2020
DOI: 10.1101/2020.03.02.971036
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Investigation of Codon Alternation Patterns in Genetic Diseases through Numerical Representation and Codon Classification

Abstract: Motivation: Alteration of amino acid is possible due to mutation in codons that could have a potential impact in a diseased condition. Effective mutation analysis can help to predict the fate of the diseased individual which can be validated later by in-vitro experimentations. It may also help an individual who is asymptomatic but having a particular genetic change for early detection and diagnosis during any terminal diseases. We try to investigate the codon alteration patterns and its impact during mutation … Show more

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