Investigation of cold-active and mesophilic cellulases: opportunities awaited

Chavan, Sambhaji B.; Shete, Ashvini M.; Mirza, Yasmin; Dharne, Mahesh

doi:10.1007/s13399-021-02047-y

Cited by 6 publications

(1 citation statement)

References 252 publications

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“…Meanwhile, metabolites generated during the fermentation process may inhibit enzyme activities in the saccharification process [31]. To address these issues, many works of research are focusing on enzyme optimization and fermentative microorganism screening to ensure both of them can work efficiently under the same conditions [179][180][181][182][183]. Co-cultures of multiple microorganism strains are also often applied in SSF [184][185][186].…”

Section: Lignocellulose Hydrolysate In Different Biorefinery Strategiesmentioning

confidence: 99%

Composition of Lignocellulose Hydrolysate in Different Biorefinery Strategies: Nutrients and Inhibitors

Wang,

Zhang,

Cui

et al. 2024

Molecules

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The hydrolysis and biotransformation of lignocellulose, i.e., biorefinery, can provide human beings with biofuels, bio-based chemicals, and materials, and is an important technology to solve the fossil energy crisis and promote global sustainable development. Biorefinery involves steps such as pretreatment, saccharification, and fermentation, and researchers have developed a variety of biorefinery strategies to optimize the process and reduce process costs in recent years. Lignocellulosic hydrolysates are platforms that connect the saccharification process and downstream fermentation. The hydrolysate composition is closely related to biomass raw materials, the pretreatment process, and the choice of biorefining strategies, and provides not only nutrients but also possible inhibitors for downstream fermentation. In this review, we summarized the effects of each stage of lignocellulosic biorefinery on nutrients and possible inhibitors, analyzed the huge differences in nutrient retention and inhibitor generation among various biorefinery strategies, and emphasized that all steps in lignocellulose biorefinery need to be considered comprehensively to achieve maximum nutrient retention and optimal control of inhibitors at low cost, to provide a reference for the development of biomass energy and chemicals.

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