The recent progresses in plasma assisted low temperature combustion, in-situ Mid-IR diagnostics, and kinetic mechanism development are presented. The observations of plasma and ozone activated new flame regimes such as the self-sustaining cool diffusion flames, cool premixed flames, and mild combustion are reported. The direct measurements of intermediate species and the kinetic pathways of low temperature ethylene oxidation in a non-equilibrium plasma reactor are presented. The recent development and validation of a high pressure kinetic mechanism for plasma assisted combustion (HP-Mech/plasma) are discussed. Technical challenges and future research needs are summarized.