Investigation of cone-beam acquisitions implemented using a novel dedicated mammotomography system with unique arbitrary orbit capability (Honorable Mention Poster Award)

McKinley, Randolph L.; Bryzmialkiewicz, Caryl N.; Madhav, Priti; Tornai, Martin P.

doi:10.1117/12.596089

Cited by 22 publications

(27 citation statements)

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“…As has been demonstrated by us, this also leads to more nearly complete sampling throughout a larger object FOV. 8,26,27,41,44 In both cases, due to the symmetrical nature of the orbits about the 3D center of rotation (COR), the dose deposition in the volume is approximately radially symmetric. This is easily seen in the coronal Monte Carlo results [ Fig.…”

Section: Discussionmentioning

confidence: 99%

Three dimensional dose distribution comparison of simple and complex acquisition trajectories in dedicated breast CT

et al. 2015

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Purpose: A novel breast CT system capable of arbitrary 3D trajectories has been developed to address cone beam sampling insufficiency as well as to image further into the patient's chest wall. The purpose of this study was to characterize any trajectory-related differences in 3D x-ray dose distribution in a pendant target when imaged with different orbits. Methods: Two acquisition trajectories were evaluated: circular azimuthal (no-tilt) and sinusoidal (saddle) orbit with ±15• tilts around a pendant breast, using Monte Carlo simulations as well as physical measurements. Simulations were performed with tungsten (W) filtration of a W-anode source; the simulated source flux was normalized to the measured exposure of a W-anode source. A water-filled cylindrical phantom was divided into 1 cm 3 voxels, and the cumulative energy deposited was tracked in each voxel. Energy deposited per voxel was converted to dose, yielding the 3D distributed dose volumes. Additionally, three cylindrical phantoms of different diameters (10, 12.5, and 15 cm) and an anthropomorphic breast phantom, initially filled with water (mimicking pure fibroglandular tissue) and then with a 75% methanol-25% water mixture (mimicking 50-50 fibroglandular-adipose tissues), were used to simulate the pendant breast geometry and scanned on the physical system. Ionization chamber calibrated radiochromic film was used to determine the dose delivered in a 2D plane through the center of the volume for a fully 3D CT scan using the different orbits. Results: Measured experimental results for the same exposure indicated that the mean dose measured throughout the central slice for different diameters ranged from 3.93 to 5.28 mGy, with the lowest average dose measured on the largest cylinder with water mimicking a homogeneously fibroglandular breast. These results align well with the cylinder phantom Monte Carlo studies which also showed a marginal difference in dose delivered by a saddle trajectory in the central slice. Regardless of phantom material or filled fluid density, dose delivered by the saddle scan was negligibly different than the simple circular, no-tilt scans. The average dose measured in the breast phantom was marginally higher for saddle than the circular no tilt scan at 3.82 and 3.87 mGy, respectively. Conclusions: Not only does nontraditional 3D-trajectory CT scanning yield more complete sampling of the breast volume but also has comparable dose deposition throughout the breast and anterior chest volume, as verified by Monte Carlo simulation and physical measurements. C 2015 American Association of Physicists in Medicine. [http://dx

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Section: Discussionmentioning

confidence: 99%

Three dimensional dose distribution comparison of simple and complex acquisition trajectories in dedicated breast CT

et al. 2015

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“…Due to the failure to meet this condition with a wide cone-beam, reconstruction of slices for locations further away from the flat plane of the beam (which is parallel to the ground and intersects the focal point) contains significant distortion and errors. This incompleteness in circular trajectories with cone-beam acquisitions has been seen to degrade the reconstructed images, especially with the use of large cone angles (Webb et al 1987, Kudo and Saito 1990, Davis 2005, McKinley et al 2005a. Figure 5 (bottom left) illustrates the cause of the insufficient sampling in our experimental setup.…”

Section: Disk Phantom Without Acrylic Ballsmentioning

confidence: 99%

“…Various groups that have developed cone-beam dedicated breast CT tomographic scanners have also been limited to using a circular scan during image acquisition (Chen and Ning 2002, Vedula and Glick 2003, Chen et al 2005, Boone et al 2006. This limits the CT system in its ability to image deep into the breast and chest wall, and introduces insufficient sampling which has previously been shown to be eliminated by using 3D complex acquisition trajectories (Kudo and Saito 1990, Zeng et al 1994, Junhai et al 2003, McKinley et al 2005a. In this study, we describe the configuration of the dual-modality SPECT-CT system and evaluate the effects on object distortion with the CT system at different stationary tilts.…”

Section: Introductionmentioning

confidence: 99%

“…With the compact, high performance gamma camera of the SPECT system and the novel quasi-monochromatic x-ray cone-beam of the CT system (McKinley et al 2005b), both systems have independently yielded visualization of small lesions in the breast, especially ones closer to the chest wall. Each system was first developed on its own 3D positioning gantry which permitted simultaneous azimuthal and polar tilting motion capabilities , McKinley et al 2005a. This allowed the source-detector combinations to be positioned anywhere in a hemisphere about a pendant, uncompressed breast during a tomographic acquisition.…”

Section: Introductionmentioning

confidence: 99%

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Optimizing and Evaluating an Integrated SPECT-CmT System Dedicated to Improved 3-D Breast Cancer Imaging

Crotty¹

2009

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“…Improvement of patient positioning is necessary to optimize the inclusion of the breast tissue up to the chest wall. 8 Typically, two parameters are used for evaluating breast coverage: the visibility of anatomical points described by O'Connell et al 9 and the volume and length of the breast in the field of view below the patient table. 10 With the help of those parameters, it is also possible to evaluate breast tissue coverage for different patient positions and to accommodate other influences such as a patient's breathing.…”

Section: Introductionmentioning

confidence: 99%

Optical measurement of dimensional parameters of the breast with subjects in prone position

Roessler

Althoff²,

Jaeger³

et al. 2015

J. Med. Imag

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Abstract. Various applications require information on breast parameters, such as breast length and volume. An optical system was designed and tested for measuring these parameters with subjects in a prone position. The study results were used for optimizing patient positioning and handling for a future breast computed tomography (BCT) system. Measurements were conducted using an optical measurement system. To test the functionality and accuracy of the system, measurements were performed using reference phantoms. Additionally, 20 women and 5 men were examined to calculate breast parameters in alternative positions and breathing states. The results of the optical measurements were compared with magnetic resonance imaging (MRI) measurements. Volume and length of the reference phantoms were determined with errors below 2%. The patient study demonstrated a mean breast volume of 530.7 ml for women during normal breathing. During an exhalation state, breast volume increased significantly by 17.7 ml in comparison with normal breathing. Differences with MRI measurements were found to be 3% for breast length and 9% for breast volume on average. The proposed optical measurement system was found to be suitable for measuring the dimensional parameters of the breast in a prone position and provides a tool for evaluating breast coverage for BCT.

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Investigation of cone-beam acquisitions implemented using a novel dedicated mammotomography system with unique arbitrary orbit capability (Honorable Mention Poster Award)

Cited by 22 publications

References 0 publications

Three dimensional dose distribution comparison of simple and complex acquisition trajectories in dedicated breast CT

Three dimensional dose distribution comparison of simple and complex acquisition trajectories in dedicated breast CT

Optimizing and Evaluating an Integrated SPECT-CmT System Dedicated to Improved 3-D Breast Cancer Imaging

Optical measurement of dimensional parameters of the breast with subjects in prone position

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