The paper presents a novel approach towards developing fatigue design curve under combined loading involving low cycle fatigue (LCF) and high cycle fatigue (HCF), in a type 316LN austenitic stainless steel. The total strain life curve used for fatigue design is modified taking into account the effect of varying load history. The methodology relies on the test data obtained to previous studies by authors pertaining to LCF‐HCF interaction using a sequential pattern at 923 K. Modified design curves are generated at 923 K where the effect of varying degree of prior LCF exposure at strain range of 0.12% is accounted for, on HCF.