1964
DOI: 10.1136/bmj.1.5396.1470
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Investigation of Failure of Artificial Pacing

Abstract: a completely successful mitral valvotomy, or repair of an atrial septal defect, it is probably no longer needed. The effectiveness of quinidine, after conversion with direct-current shock, to lessen the relapse rate is being further studied.No complication in the present series has been serious. Extreme care is required and proper insulation of the apparatus is essential, especially when used at the time of thoracotomy. Ventricular tachycardia and fibrillation after direct-current shock in dogs appear to be re… Show more

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Cited by 18 publications
(1 citation statement)
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“…In treating 19 of our early patients a number of prototype units were tried, some from outside with only a receiver unit implanted, and others containing their own battery for power; some could be turned on and off, speeded up, and slowed down from outside. However, as a result of experimental work done in this hospital (Sowton, 1963), an early decision was taken to concentrate on the development of a fixed-rate pacemaker powered by miniature mercury cells within the implanted unit. There was no time for prolonged laboratory or animal trials since patients with complete heart block in whom Stokes-Adams attacks threatened life required pacing without delay.…”
mentioning
confidence: 99%
“…In treating 19 of our early patients a number of prototype units were tried, some from outside with only a receiver unit implanted, and others containing their own battery for power; some could be turned on and off, speeded up, and slowed down from outside. However, as a result of experimental work done in this hospital (Sowton, 1963), an early decision was taken to concentrate on the development of a fixed-rate pacemaker powered by miniature mercury cells within the implanted unit. There was no time for prolonged laboratory or animal trials since patients with complete heart block in whom Stokes-Adams attacks threatened life required pacing without delay.…”
mentioning
confidence: 99%