Investigation of gestational diabetic lipid levels

Abstract

Aim: Abnormal lipid profiles have been associated with gestational diabetes mellitus (GDM). We aimed to investigate the lipid profile in gestational diabetes. Material and Method:This study was included 127 GDM and 30 healthy pregnant women to control group, similar body mass indeks (BMI), gestational week and age group. Total cholesterol, high-density lipoprotein (HDL-C) plasma concentrations were measured by cholesterol enzymatic tests. Low-density lipoprotein cholesterol (LDL-C) was calculated using Friedewald's formula.Results: Triglyceride, total cholesterol, and LDL-C levels were found to be increased in pregnancy. However, it was not statistically significant. GDM compared with the control group in HDL-C were statistically significantly lower. When logistic regression was performed, HDL was lower than GDM control, regardless of age, BMI, gestational week. When Roc analysis was performed, it was seen that HDL <70 mg / dL GDM was predicted with 83% specificity and 64% sensitivity. Conclusion:Low HDL-C concentrations were significantly associated with an increased risk of GDM. Total cholesterol, LDL-C, TG values were not significantly elevated.