Investigation of<i>Cassia alata</i>, a Plant Used in Nigeria in the Treatment of Skin Diseases

Benjamin, T. V.; Lamikanra, Adebayo

doi:10.3109/13880208109070583

Cited by 29 publications

(18 citation statements)

References 3 publications

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“…MBC was undetected for E. coli with Recinnus communis extracts; P. aeruginosa however indicated low MIC and MBC (Table 3 & 4). All the extracts showed inhibitory activities against skin and wound disease-causing pathogens used as demonstrated by similar works [5,14,[19][20][21][22][23]. The efficacy of the plant extracts provide a scientific basis and thus validates their traditional use in the treatment of skin and wound diseases associated with these bacteria.…”

Section: In Vitro Bacteriostatic and Bactericidal Activities Of Sennasupporting

confidence: 52%

In Vitro Bacteriostatic and Bactericidal Activities of Senna alata, Ricinus communis and Lannea barteri extracts Against Wound and Skin Disease Causing Bacteria

Donkor¹

2016

JAPLR

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Antibacterial activities of the extracts of three medicinal plants, Senna alata, Ricinus communis and Lannea barteri from two different extractants were studied. Bacteria strains such as Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli are known wound and skin disease causing bacteria. For 100g of each plant material, the percentage yields of the extracts were determined and ranged between 5.20% and 12.40%. Phytochemical screening of the crude extracts of Senna alata, Ricinus communis and Lannea barteri revealed the presence of some bioactive components, including tannins, anthraquinones, saponins, flavonoids and alkaloids. All plant extracts showed inhibition on test organisms and were in the range of 12.0 ± 2.83mm to 36.0 ± 2.12mm for all the extracts. The MIC values obtained for the entire test ranged from 3.13mg/ml to 12.50mg/ml and MBC values were found to be 200mg/ml minimum and 400mg/ml maximum. Findings support the traditional use of Senna alata, Ricinus communis and Lannea barteri for the treatment of skin and wound infections and form a strong basis for further exploration of these plants.

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Section: In Vitro Bacteriostatic and Bactericidal Activities Of Sennasupporting

confidence: 52%

In Vitro Bacteriostatic and Bactericidal Activities of Senna alata, Ricinus communis and Lannea barteri extracts Against Wound and Skin Disease Causing Bacteria

Donkor¹

2016

JAPLR

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“…[24] These phytoconstituents are also known to possess surface activity and other soap-related properties. In previous studies, Cassia alata has been found to possess excellent wound-healing properties [25,26]. The water-soluble ingredients present in the extract are responsible for the reduction of metal ions and efficient stabilization of nanoparticles.…”

Section: Resultsmentioning

confidence: 99%

“…The leaves are extensively used against dermatophyte infections, such as 'tidea foot,' popularly known as 'athlete foot', for superficial mycoses and also in the treatment of chronic fungal infections such as 'pityriasis versicolor'. They are used externally for the treatment of skin disease, acne, tinea infections, insect bites, ringworms, eczema, scabies, itchiness, and internally as expectorant for bronchitis, for alleviation of asthma symptoms, as a laxative to expel intestinal parasites, for stomach problems and weight loss [24][25][26]. In the present study, Cassia alata was used for the synthesis of silver nanoparticles by the green route and characterized by spectral analysis.…”

Section: Introductionmentioning

confidence: 99%

Efficient and robust biofabrication of silver nanoparticles by cassia alata leaf extract and their antimicrobial activity

et al. 2014

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Biosynthesis of green nanomaterials and their characterization comprise an emerging field of nanotechnology, due to their wide range of applications. The present study deals with the synthesis of silver nanoparticles (AgNPs) using an aqueous leaf extract of Cassia alata. The AgNPs are characterized using UV-Visible spectroscopy. The surface plasmon resonance spectrum of AgNPs was obtained at 434 nm, and scanning electron microscopy coupled with X-ray energy dispersive spectroscopy (EDX) data revealed that AgNPs were uniformly spherical in shape. EDX data show very strong silver signal and weak signals to other elements, and X-ray diffraction patterns reveal that the particles are crystalline in nature with facecentered cubic structure. Fourier transform-infrared spectroscopy reveals that the carbonyl group (C = O, 1637.07 cm -1 ) is involved in the reduction of Ag ? to Ag. The synthesized AgNPs were crystalline in nature and spherical in shape, with an average of [41 nm size. The stability of AgNPs is due to its high negative zeta potential, which is -50.7 mV. Further, atomic force microscopy studies also revealed that the average particle size was 47 nm which correlates with the above result of particle size analysis. The present study also indicates that AgNPs have considerable antibacterial activity and exceptionally superior antifungal activity, in comparison with standard antimicrobial drugs.

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“…-The bath of fresh leaves of Senna alata (L.) Roxb. to treat skins ailments (Benjamin and Lamikanra, 1981;Caceres et al, 1991b;Palanichamy et al, 1991;Fiallo and Vasquez Tineo, 1992;Damodaran and Venkataraman, 1994;Lopez et al, 2005;Martinez et al, 2005c) is a notable TRAMIL plant use in Guatemala (Giron, 1988), Venezuela (Delens, 1990-92), Martinique (Longuefosse and Nossin, 1990-95), Dominican Republic (Castillo et al, 2003), Saint-Vincent (Balland et al, 2004) and Tobago (Delaigue, 2005).…”

Section: Discussionmentioning

confidence: 99%

TRAMIL ethnopharmalogical survey in Les Saintes (Guadeloupe, French West Indies): A comparative study

Boulogne

Germosén-Robineau

Ozier‐Lafontaine

et al. 2011

Journal of Ethnopharmacology

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Investigation ofCassia alata, a Plant Used in Nigeria in the Treatment of Skin Diseases

Cited by 29 publications

References 3 publications

In Vitro Bacteriostatic and Bactericidal Activities of Senna alata, Ricinus communis and Lannea barteri extracts Against Wound and Skin Disease Causing Bacteria

In Vitro Bacteriostatic and Bactericidal Activities of Senna alata, Ricinus communis and Lannea barteri extracts Against Wound and Skin Disease Causing Bacteria

Efficient and robust biofabrication of silver nanoparticles by cassia alata leaf extract and their antimicrobial activity

TRAMIL ethnopharmalogical survey in Les Saintes (Guadeloupe, French West Indies): A comparative study

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