Investigation of Interactional Behavior of some Biologically Important Compounds by a Quantitative Method

Abstract

The features of surrounding environment of biologically interesting compounds can play key role in their function in various phenomena. Environment effects are usually studied qualitatively, but this method cannot give precise information about the interactional behavior of under study molecules. In this case, a quantitative interpretation can give useful information about the behavior of selected samples in various environments. In this work, spectroscopic technique was used for investigation of media effects on the linear optical properties of some drugs. The quantitative experimental results indicate that specific and nonspecific interactions with different contributions can modify the linear optical properties of folic acid, folinic acid and methotrexate drugs with different substituent in their chemical structures that these quantitative results can expand to the various groups of biological important compounds.