The microstructure and properties of Al-matrix composites are directly determined by ceramic particles in the matrix, such as synthetic methods, morphologies, sizes, interface, etc., especially the distribution of particles. Hereinto, Al-matrix nanocomposites, which show brilliant, comprehensive properties, have been widely studied. How to give full play to its advantages in further applications in automotive and aerospace areas has attracted considerable attention from researchers. In this review, current development on the pre-distribution of reinforcement particles and deformation processes and microstructure, mechanical properties of Al-matrix composites reinforced with in-situ and ex-situ nanoparticles will be addressed. In addition, the corresponding development prospects and challenges of nanoparticles reinforced Al-matrix composites fabricated by a combination of pre-distribution and deformation were also summarised.