“…Hand-in-hand with the generation of experimental findings, mathematical and engineering techniques have been applied to carry out in depth data analysis. Models of secondary osteons and lamellae have been developed to reflect their multi-directional structures so as to investigate the functions of the elementary components when they are under different loading conditions (7,110,150,151,152,153,154,155,156,157,158,159,160,161,162,163,164,165,166,167).…”