BackgroundHeat sensitivity of phenolics and flavonoids leads to considerable losses in these compounds during conventional drying. Microwave drying has advantage of shorter drying time and rigorous process control, minimizing damage to heat sensitive compounds. Microwave drying kinetics and impacts of microwave drying on physicochemical characteristics, morphological structure, antioxidant properties, total phenolics and flavonoids of propolis extract were investigated.ResultsIncreasing the microwave power output from 180 to 900 W resulted in a 67% reduction in drying time. Morphological changes were more noticeable at higher microwave power levels as shown in scanning electron microscopy images. Water activity values of microwave dried propolis extracts were below 0.4, which satisfied the requirement of shelf stable dry products. Solubility of microwave dried propolis extract increased by increasing the microwave power level, and the highest solubility was achieved for the propolis extract microwave dried at 900 W. Microwave dried propolis extracts exhibited lower total phenolic content values than the fresh propolis extract. Microwave power level did not affect total flavonoid content, but it affected 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) free radical scavenging activities of microwave dried propolis extracts. The DPPH free radical scavenging activity closest to the fresh propolis extract was obtained for the microwave dried propolis extract at 900 W, which also showed the highest trolox equivalent antioxidant capacity.ConclusionMicrowave drying of propolis extract at 900 W was found to be the most efficient drying condition because it yielded the shortest drying time, the highest Deff and highly identical phenolics and flavonoids as compared to fresh propolis extract.This article is protected by copyright. All rights reserved.