Investigation of modifier effects in supercritical CO2 extraction from various solid matrices

Supercritical Fluid Extraction of Bioactive Compounds: Fundamentals, Applications and Economic Perspectives

“…Goto et al (1998) evaluated the SC-CO 2 extraction of peppermint essential oil in which the solute seems to interact strongly with the solid matrix. Other studies corroborate (Papamichail et al 2000) with the premise of the solute-solid matrix interaction (Goto et al 1993;Jeong and Chesney 1999;Murga et al 2000;Sovová et al 1994;Sovová 2005). The absorption of compounds on the solid matrix and the localization of the compounds to be extracted inside to complex solid structure are the main causes affecting the solubility of compounds in SCF.…”

Extraction of boldo (Peumus boldus M.) leaves with supercritical CO2 and hot pressurized water

“…Thus, the yield of boldine depends more pronouncedly on these two variables than that of other components in the extract. This may be due to preferential interactions between boldine and ethanol, and/or disruption of the interaction between boldine and the solid matrix (Jeong & Chesney, 1999). Yield in experiments with high-pressure CO 2 and ethanol may be also affected by mass transfer factors, and binding of solutes to the solid matrix.…”

Optimization of process variables for phyllanthin extraction from Phyllanthus amarus leaves by supercritical fluid using a Box-Behnken experimental design followed by HPLC identification

“…Addition of a small amount of polar organic solvent (co-solvent) to the supercritical CO 2 can remarkably increase the extractability of target analytes. Various polar co-solvents have been tried over the years for the supercritical CO 2 extraction of polar constituents, but methanol has remained the most popular (30). Since the nature of the co-solvent may influence extraction yield and selectivity, three different co-solvents, viz,.…”