Investigation of photoplethysmographic signals and blood oxygen saturation values obtained from human splanchnic organs using a fiber optic sensor

Hickey, Michelle J.; Samuels, N.; Randive, N.; Langford, R. M.; Kyriacou, Panayiotis A.

doi:10.1007/s10877-011-9302-4

Cited by 10 publications

(4 citation statements)

References 13 publications

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“…5 PPG has found its utility in a vast number of applications, such as neonatal care, hemorheology assessment, pulse transit time investigation, and measurements from body cavities and organs. [6][7][8][9][10][11][12] Near-infrared spectroscopy (NIRS) is another noninvasive optical technique, which measures variations in local blood perfusion by estimating changes in oxy-hemoglobin, deoxyhemoglobin, and total hemoglobin. 13 These physiological variables are determined using the Beer-Lambert law, correlating the attenuation of light A, through a medium with the concentration C of the absorber (chromophore) present in the solution.…”

Section: Introductionmentioning

confidence: 99%

Investigating optical path and differential pathlength factor in reflectance photoplethysmography for the assessment of perfusion

et al. 2018

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Photoplethysmography (PPG) is an optical noninvasive technique with the potential for assessing tissue perfusion. The relative time-change in the concentration of oxyhemoglobin and deoxyhemoglobin in the blood can be derived from DC part of the PPG signal. However, the absolute concentration cannot be determined due to the inadequate data on PPG optical paths. The optical path and differential pathlength factor (DPF) for PPG at red (660 nm) and infrared (880 nm) wavelengths were investigated using a heterogeneous Monte Carlo model of the human forearm. Using the simulated DPFs, the absolute time-change in concentrations were determined from PPG signals recorded from the same tissue site. Results were compared with three conditions of approximated DPFs. Results showed the variation of the optical-path and DPF with different wavelengths and source-detector separations. Approximations resulted in significant errors, for example, using NIRS DPF in PPG led to "cross talk" of -0.4297 and 0.060 and an error of 15.16% to 25.18%. Results confirmed the feasibility of using the PPG (DC) for the assessment of tissue perfusion. The study also identified the inappropriateness of the assumption that DPF is independent of wavelength or source-detector separations and set the platform for further studies on investigating optical pathlengths and DPF in PPG.

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Section: Introductionmentioning

confidence: 99%

Investigating optical path and differential pathlength factor in reflectance photoplethysmography for the assessment of perfusion

et al. 2018

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“…(3) When the sodium coating of the dialysate is lower than the sodium coating of the plasma, the osmotic pressure of the patients' plasma drops, and the water in the blood enters the cells extracellularly, which causes a sharp decrease in effective blood volume. This is the main reason for an early drop in blood pressure during hemodialysis treatment [1][2][3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Autonomic Nerve Activation Observed for Hemodialysis Patients While Squeezing a Soft Ball

et al. 2020

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In this study, a medical grade pulse rate (PR) instrument was used to monitor hemodialysis patients, and the wearable product was applied for the 4 h observation. Electrocardiogram (ECG) and photoplethysmography (PPG) data were simultaneously collected to observe physiological phenomena in patients undergoing hemodialysis. The analyzed results of 38 patients undergoing the treatment (as sympathetic/parasympathetic balance indicators before-hemodialysis (HD), and after-HD) and autonomic nerve activation for the pulse rate (PR) measurement accompanied by squeezing a soft ball were also observed. The results prove the pulse rate measurement while squeezing the soft ball and analyze data, and we show that the analyzed results have a very concentrated normal distribution. This study presents oxygen saturation (SpO2) and continuous pulse rate distribution curves during the 4 h observation of the hemodialysis patients and we show that some patients undergoing kidney dialysis have sleep apnea. They become lethargic during dialysis and experience severe hypoxia due to intermittent respiratory arrest. Studies have confirmed that such monitoring and biofeedback designs can reduce the incidence of hypotension during dialysis.

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“…These newly derived variables are now being used as diagnostic markers for conditions such as arterial stiffness [9], hypertension, peripheral vascular disease [10], stress, endothelial dysfunction [11], and haemorheology [12]. Furthermore, PPG has generated immense interest in the development of unique sensor technology utilizing either miniaturized optoelectronic components or optical fibers, to measure the volumetric changes directly from organs such as the esophagus [13], liver, bowel [14], brain [15], ear canal [10], and other vascular tissues such as free flaps [16]. In the last few years, PPG has also found its place in the remote health monitoring market.…”

Section: Introductionmentioning

confidence: 99%

Design and Development of a Modular, Multichannel Photoplethysmography System

Budidha

Rybynok

Kyriacou

2018

IEEE Trans. Instrum. Meas.

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In this paper, we present the design, development, and validation of a 'modular photoplethysmography (PPG) system called ZenPPG. This portable, dual-channel system has the capability to produce "raw" PPG signals at two different wavelengths using commercial and/or custom-made PPG sensors. The system consists of five modules, each consisting of circuitry required to perform specific tasks, and are all interconnected by a system bus. The ZenPPG system also facilitates the acquisition of other physiological signals on-demand including electrocardiogram (ECG), respiration, and temperature signals. This report describes the technical details and the evaluation of the ZenPPG along with results from a pilot in vivo study on healthy volunteers. The results from the technical evaluations demonstrate the superiority and flexibility of the system. Also, the systems' compatibility with commercial pulse oximetry sensors such as the Masimo reusable sensors was demonstrated, where good quality raw PPG signals were recorded with the signal-to-noise ratio (SNR) of 50.65 dB. The estimated arterial oxygen saturation (SpO 2) values from the system were also in close agreement with commercial pulse oximeters, although the accuracy of the reported SpO 2 value is dependent on the calibration function used. Future work is targeted toward the development of variations of each module, including the laser driver and fiber optic module, onboard data acquisition and signal processing modules. The availability of this system will help researchers from a wide range of disciplines to customize and integrate the ZenPPG system to their research needs and will most definitely enhance research in related fields.

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Investigation of photoplethysmographic signals and blood oxygen saturation values obtained from human splanchnic organs using a fiber optic sensor

Cited by 10 publications

References 13 publications

Investigating optical path and differential pathlength factor in reflectance photoplethysmography for the assessment of perfusion

Investigating optical path and differential pathlength factor in reflectance photoplethysmography for the assessment of perfusion

Autonomic Nerve Activation Observed for Hemodialysis Patients While Squeezing a Soft Ball

Design and Development of a Modular, Multichannel Photoplethysmography System

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