2013
DOI: 10.1007/s10967-012-2403-9
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Investigation of production routes for the 161Ho Auger-electron emitting radiolanthanide, a candidate for therapy

Abstract: The radiolanthanide 161 Ho (2.48 h) is a promising Auger-electron emitter for internal radiotherapy that can be produced with particle accelerators. The excitation functions of the nat Dy(p,xn) 161 Ho and nat Dy(d,x) 161 Ho reactions were measured up to 40 and 50 MeV respectively by using the stacked foil activation method and -ray spectrometry. The experimental data were compared with results of the TALYS code available in the TENDL 2011 library [1]. The main parameters of different production routes are disc… Show more

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Cited by 17 publications
(10 citation statements)
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“…These measurements are higher than the theoretical calculations; however, the measurements given by Takacs et al [38], Khandaker et al [39], and Scholten et al [33] are close to the theoretical excitation curve. The agreement between the experimental data [40,41] and MLD in the energy range below 12 and above 20 MeV is good. The data reported by Alharbi et al [42] are in good agreement with the MLD beyond 18 MeV.…”
Section: Production Of the Radioisotope 99m Tcsupporting
confidence: 64%
“…These measurements are higher than the theoretical calculations; however, the measurements given by Takacs et al [38], Khandaker et al [39], and Scholten et al [33] are close to the theoretical excitation curve. The agreement between the experimental data [40,41] and MLD in the energy range below 12 and above 20 MeV is good. The data reported by Alharbi et al [42] are in good agreement with the MLD beyond 18 MeV.…”
Section: Production Of the Radioisotope 99m Tcsupporting
confidence: 64%
“…[6,7,8,9]). Here we present shortly the most important facts, and details specific for this experiment.…”
Section: Methodsmentioning
confidence: 99%
“…The cross section data for this reaction have been thoroughly measured [cf. [14][15][16] and evaluated [17], so that the database is now reliable. However, for a critical check of the impurities associated with this process as well as for development of other possible production routes, further extensive nuclear data studies are necessary.…”
Section: Diagnostic Radionuclidesmentioning
confidence: 99%