Investigation of renal lesions by diffusion-weighted magnetic resonance imaging applying intravoxel incoherent motion-derived parameters—Initial experience

Rheinheimer, Stephan; Stieltjes, Bram; Schneider, Frank; Simon, Dirk; Pahernik, Sascha; Kauczor, Hans‐Ulrich; Hallscheidt, Peter

doi:10.1016/j.ejrad.2011.10.016

Cited by 87 publications

(76 citation statements)

References 20 publications

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“…However, MRI can also provide physiological information such as the perfusion fraction, an in‐vivo estimate of the volume fraction of perfused tissue13, 14, 15, the examination for which can be performed within minutes. Previous studies have investigated the placental perfusion fraction in vivo 16, 17, 18, 19.…”

Section: Introductionmentioning

confidence: 99%

Magnetic resonance imaging‐estimated placental perfusion in fetal growth assessment

Sohlberg

Mulic‐Lutvica

Olovsson

et al. 2015

Ultrasound in Obstet & Gyne

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ObjectiveTo evaluate in‐vivo placental perfusion fraction, estimated by magnetic resonance imaging (MRI), as a marker of placental function.MethodsA study population of 35 pregnant women, of whom 13 had pre‐eclampsia (PE), were examined at 22–40 weeks' gestation. Within a 24‐h period, each woman underwent an MRI diffusion‐weighted sequence (from which we calculated the placental perfusion fraction), venous blood sampling and an ultrasound examination including estimation of fetal weight, amniotic fluid index and Doppler velocity measurements. The perfusion fractions in pregnancies with and without fetal growth restriction were compared and correlations between the perfusion fraction and ultrasound estimates and plasma markers were estimated using linear regression. The associations between the placental perfusion fraction and ultrasound estimates were modified by the presence of PE (P < 0.05) and therefore we included an interaction term between PE and covariates in the models.ResultsThe median placental perfusion fractions in pregnancies with and without fetal growth restriction were 21% and 32%, respectively (P = 0.005). The correlations between placental perfusion fraction and ultrasound estimates and plasma markers were highly significant (P = 0.002 and P = 0.0001, respectively). The highest coefficient of determination (R 2 = 0.56) for placental perfusion fraction was found for a model that included pulsatility index in the ductus venosus, plasma level of soluble fms‐like tyrosine kinase‐1, estimated fetal weight and presence of PE.ConclusionThe placental perfusion fraction has the potential to contribute to the clinical assessment of cases with placental insufficiency. © 2015 Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

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Section: Introductionmentioning

confidence: 99%

Magnetic resonance imaging‐estimated placental perfusion in fetal growth assessment

Sohlberg

Mulic‐Lutvica

Olovsson

et al. 2015

Ultrasound in Obstet & Gyne

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“…It is noteworthy that diffusion-weighted imaging (DWI), combined with various mathematical models, was reported as an effective technique in some studies (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). Currently, the monoexponential DWI refers to a widely used mathematical model of clinical DWI.…”

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confidence: 99%

“…Thus, a precise diagnosis of preoperative Fuhrman grade becomes sufficiently important. As noninvasive assessment modalities, computed tomography (CT) and magnetic resonance imaging (MRI) have been used to determine therapeutic strategies and surgical planning in RCC (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18).…”

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confidence: 99%

Comparison of biexponential and monoexponential DWI in evaluation of Fuhrman grading of clear cell renal cell carcinoma

Liu¹,

Yang²

2017

Diagn Interv Radiol

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“…The apparent diffusion coefficient (ADC) is an important index that is measured during DWI. In recent years, follow-up DWI has been increasingly employed in imaging the abdominal organs, breast, pancreas, liver and kidney (12)(13)(14)(15)(16). DWI provides functional information through three parameters: The dispersion diagram, the ADC diagram and the ADC value, which has gained significant attention due to its role in tumor diagnosis (17).…”

Section: Introductionmentioning

confidence: 99%

Diagnostic utility of diffusion-weighted magnetic resonance imaging in two common renal tumors

2015

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Abstract. The aim of the present study was to evaluate the utility of diffusion-weighted magnetic resonance imaging (DWI) in the diagnosis of common renal tumors. Conventional magnetic resonance imaging and DWI were performed on 85 patients with renal lesions (54 renal carcinoma and 31 renal angiomyolipoma cases). The apparent diffusion coefficient (ADC) values in each case at b=800 sec/mm 2 were measured in the ADC maps using a statistical software package. The 54 cases of renal cell carcinoma showed a high signal intensity in the parenchyma, and the 31 renal angiomyolipoma cases showed a well-defined mixed signal intensity on DWI. The soft-tissue component showed a high signal intensity and the fat tissue showed a low signal intensity on DWI. When the b-value was set to 800 sec/mm 2 , the mean ADC was significantly lower in the renal carcinoma cases than in the renal angiomyolipoma cases. In conclusion, the measurement of ADC on DWI can reveal the structure of renal tumors, which is beneficial in diagnosing and determining the prognosis of benign and malignant renal tumors.

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Investigation of renal lesions by diffusion-weighted magnetic resonance imaging applying intravoxel incoherent motion-derived parameters—Initial experience

Cited by 87 publications

References 20 publications

Magnetic resonance imaging‐estimated placental perfusion in fetal growth assessment

Magnetic resonance imaging‐estimated placental perfusion in fetal growth assessment

Comparison of biexponential and monoexponential DWI in evaluation of Fuhrman grading of clear cell renal cell carcinoma

Diagnostic utility of diffusion-weighted magnetic resonance imaging in two common renal tumors

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