1999
DOI: 10.1088/0031-9155/44/12/302
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Investigation of scattered radiation in 3D whole-body positron emission tomography using Monte Carlo simulations

Abstract: The correction of scattered radiation is one of the most challenging tasks in 3D positron emission tomography (PET) and knowledge about the amount of scatter and its distribution is a prerequisite for performing an accurate correction. One concern in 3D PET in contrast to 2D PET is the scatter contribution from activity outside the field-of-view (FOV) and multiple scatter. Using Monte Carlo simulations, we examined the scatter distribution for various phantoms. The simulations were performed for a whole-body P… Show more

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Cited by 71 publications
(45 citation statements)
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“…This broader distribution of multiple scatter may lead to a mismatch between single and total scatter distribution. Thus, scaling of the single scatter estimation might not be an accurate approximation of the total scatter distribution, as some studies have already demonstrated [16][17][18]. Goggin and Ollinger [16] propose filtering single scatter estimation, something that is out of the focus of this study.…”
Section: Introductionmentioning
confidence: 94%
“…This broader distribution of multiple scatter may lead to a mismatch between single and total scatter distribution. Thus, scaling of the single scatter estimation might not be an accurate approximation of the total scatter distribution, as some studies have already demonstrated [16][17][18]. Goggin and Ollinger [16] propose filtering single scatter estimation, something that is out of the focus of this study.…”
Section: Introductionmentioning
confidence: 94%
“…The development of efficient Monte Carlo simulation packages has allowed the study of scatter for realistic source distributions and attenuation maps and according to a variety of physical parameters [24]. Monte Carlo calculations are widely accepted as a powerful tool for study of the spatial characteristics of scatter for various phantoms [36]. In addition, the Monte Carlo method is uniquely able to provide information about multiple versus single scatter events.…”
Section: Discussionmentioning
confidence: 99%
“…Sometimes, s depends on the estimated activity image, so more accurate scatter correction may be possible by estimating scatter during image reconstruction or艥 =艥(f (n) ). This can be implemented by using Monte Carlo (MC) simulations [70][71][72], model-based scatter estimation [32,33], or dual matrix approach [73].…”
Section: Anatomical Information For Attenuation/scatter Correction Mamentioning
confidence: 99%
“…However, in many cases, anatomical information is very important to accurately estimate scatter information along with an estimated activity image. There are many scatter estimation methods that use both anatomical image and activity image such as convolution-subtraction scatter estimation [30,69], MC based scatter estimation [31,34,[70][71][72], model-based scatter approximation [32], and single scatter simulation (SSS) [33]. Figure 1 demonstrates the importance of attenuation/scatter correction using an example of SPECT-CT in I-131 radioimmunotherapy for non-Hodgkin lymphoma.…”
Section: Sources Of Attenuation/scatter Informationmentioning
confidence: 99%