Investigation of Some Medicinal Plants from Tunisia for Antimicrobial Activities

Sassi, Ahlem Ben; Harzallah‐Skhiri, Fethia; Aouni, Mahjoub

doi:10.1080/13880200701215406

Cited by 50 publications

(25 citation statements)

References 28 publications

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“…25 Comparing results found in this study with those of the literature, we notice in a previous work on antimicrobial activity of some medicinal plants from Tunisia, that methanolic extracts of C. monspeliensis leaves have shown an interesting activity against P. aeruginosa, S. aureus, E. faecalis with inhibition zones diameters of 18.0, 20.0 and 15.0 mm, respectively. 26 Whereas, water-methanol extracts of fruit peels of pomegranate (P. granatum) have demonstrated a moderate activity when they were tested on S. aureus, P. aeruginosa and K. pneumoniae (13.0, 18.0 and 16.0 mm, respectively). 27 this activity of pomegranate peels could be attributed to tannins, for which antimicrobial activity has been demonstrated.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Antibacterial Activity of some Medicinal Plants Extracts Commonly Used in Algerian Traditional Medicine against some Pathogenic Bacteria

Bereksi¹,

Hassaïne²,

Bekhechi³

et al. 2018

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Introduction: The objective of this study was to evaluate the antibacterial activity of hydromethanolic extracts of Berberis vulgaris, Cassia angustifolia, Cinnamomum cassia, Cistus monspeliensis, Nigella sativa, Punica granatum, Rhus tripartata, Withania frutescens and Zingiber officinale against different Gram-positive and Gram-negative reference bacterial strains. Methods: The evaluation of antibacterial activity for different extracts of each plant was carried out using the disc diffusion method and determination of minimum inhibitory concentration (MIC). Results: The plant extracts showed zone of inhibition ranging from 06.0 to 23.0 mm against one or more tested bacteria, and their efficacy in terms of MICs where ranged from 0.1 to 12.8 mg/mL. The Refluxed and Macerated extracts of these plants have shown relatively similar results in terms of diameters of inhibition and MICs. The extracts of B. vulgaris, C. monspeliensis and P. granatum demonstrated relatively high activity as compared to the other plant extracts mainly against S. aureus, E. faecalis and E. cloacae. Conclusion: Findings of this study indicate that hydromethanolic extracts of these plants have antibacterial activity against the different tested bacterial strains. This activity supports their use in treatment of infections caused by such resistant bacteria.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Antibacterial Activity of some Medicinal Plants Extracts Commonly Used in Algerian Traditional Medicine against some Pathogenic Bacteria

Bereksi¹,

Hassaïne²,

Bekhechi³

et al. 2018

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“…Similarly, Shimoda et al (2012) reported that leaf extracts display antioxidant activity and promote the energy metabolism pathways in human intestinal cells, while Sayah et al (2017) reported in vivo and in vitro anti-inflammatory and analgesic capacity, as well as activities against key enzymes associated with hyperglycemia, for aerial plant parts extracts in animal studies. The extracts from leaves and flowers of C. monspeliensis also exhibited considerable antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and S. epidermidis (Papaefthimiou et al, 2014;Sassi et al, 2017). Finally, and not least important to point out is the in vitro antiproliferative and cytotoxic activity of the species against the human epithelial prostate cells and human melanoma cell line A-375 (Jemia et al, 2013;Vitali et al, 2011), as well as the activity of leaves essential oils against neurogenerative disorders (Loizzo et al, 2013).…”

Section: Health Effectsmentioning

confidence: 99%

Halophytic herbs of the Mediterranean basin: An alternative approach to health

Petropoulos

Karkanis

Martins

et al. 2018

Food and Chemical Toxicology

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Wild native species are usually grown under severe and stressful conditions, while a special category includes halophytic species that are tolerant to high salinity levels. Native halophytes are valuable sources of bioactive molecules whose content is higher in saline than normal conditions, since the adaptation to salinity mechanisms involve apart from changes in physiological functions the biosynthesis of protectant molecules. These compounds include secondary metabolites with several beneficial health effects which have been known since ancient times and used for medicinal purposes. Recent trends in pharmaceutical industry suggest the use of natural compounds as alternative to synthetic ones, with native herbs being strong candidates for this purpose due to their increased and variable content in health promoting compounds. In this review, an introductory section about the importance of native herbs and halophyte species for traditional and modern medicine will be presented. A list of the most important halophytes of the Mediterranean basin will follow, with special focus on their chemical composition and their reported by clinical and ethnopharmacological studies health effects. The review concludes by suggesting future requirements and perspectives for further exploitation of these valuable species within the context of sustainability and climate change.

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“…Flower extracts of C. monspeliensis were active against gram-positive bacteria species of genus Staphylococcus and had significant growth-inhibitory effects on Staphylococcus epidermis (Sassi et al, 2007). Furthermore, a cis -clerodane diterpene isolated in large amounts and characterized from C. monspeliensis was very active against Staphylococci species and had four times higher activity than the labdane-type diterpene sclareol (Kolocouris et al, 2001).…”

Section: Biological Functionsmentioning

confidence: 99%

Genus Cistus: a model for exploring labdane-type diterpenes' biosynthesis and a natural source of high value products with biological, aromatic, and pharmacological properties

et al. 2014

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The family Cistaceae (Angiosperm, Malvales) consists of 8 genera and 180 species, with 5 genera native to the Mediterranean area (Cistus, Fumara, Halimium, Helianthemum, and Tuberaria). Traditionally, a number of Cistus species have been used in Mediterranean folk medicine as herbal tea infusions for healing digestive problems and colds, as extracts for the treatment of diseases, and as fragrances. The resin, ladano, secreted by the glandular trichomes of certain Cistus species contains a number of phytochemicals with antioxidant, antibacterial, antifungal, and anticancer properties. Furthermore, total leaf aqueous extracts possess anti-influenza virus activity. All these properties have been attributed to phytochemicals such as terpenoids, including diterpenes, labdane-type diterpenes and clerodanes, phenylpropanoids, including flavonoids and ellagitannins, several groups of alkaloids and other types of secondary metabolites. In the past 20 years, research on Cistus involved chemical, biological and phylogenetic analyses but recent investigations have involved genomic and molecular approaches. Our lab is exploring the biosynthetic machinery that generates terpenoids and phenylpropanoids, with a goal to harness their numerous properties that have applications in the pharmaceutical, chemical and aromatic industries. This review focuses on the systematics, botanical characteristics, geographic distribution, chemical analyses, biological function and biosynthesis of major compounds, as well as genomic analyses and biotechnological approaches of the main Cistus species found in the Mediterranean basin, namely C. albidus, C. creticus, C. crispus, C. parviflorus, C. monspeliensis, C. populifolius, C. salviifolius, C. ladanifer, C. laurifolius, and C. clusii.

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Investigation of Some Medicinal Plants from Tunisia for Antimicrobial Activities

Cited by 50 publications

References 28 publications

Evaluation of Antibacterial Activity of some Medicinal Plants Extracts Commonly Used in Algerian Traditional Medicine against some Pathogenic Bacteria

Evaluation of Antibacterial Activity of some Medicinal Plants Extracts Commonly Used in Algerian Traditional Medicine against some Pathogenic Bacteria

Halophytic herbs of the Mediterranean basin: An alternative approach to health

Genus Cistus: a model for exploring labdane-type diterpenes' biosynthesis and a natural source of high value products with biological, aromatic, and pharmacological properties

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