There has been great interest in the research and development of different anti-skid and highly wear-resistant materials that can effectively reduce energy losses and improve efficiency in numerous applications. This article reviews the design, performance, and application of anti-skid and highly wear-resistant coating materials at home and abroad. First, it introduces the structure and mechanism of anti-skid and wear-resistant coatings. The preparation of different anti-slip coatings is mainly accomplished by changing the base material and anti-slip granules as well as the coating method, and the anti-slip performance is determined with the coefficient of friction test. The application mostly encompasses airplane and ocean decks, as well as pedestrian spaces. This review introduces the development status and research progress of metal-based anti-skid coatings and polymer-based anti-skid coatings, which are two groups of pavement. Finally, the challenges and future development directions of this key field are summarized and considered.