Investigation of the Direction of the Reactions of Mercaptoacetic Acid Esters With Epi- And Thioepichlorohydrins

Abstract

The reactions of mercaptoacetic acid ethers with epi- and thio-epichlorohydrin in alkaline medium have been investigated. It was found that the reaction of mercaptoacetic acid esters with epichlorohydrin in the presence of an equimolar amount of sodium hydroxide simultaneously produces 2,3-epoxy¬pro-pylalkoxycarbonylmethyl sulfides and 1-chlor-3-alkoxycarbonylmethylthiol-2-propanols. Under using sodium hydroxide is used as a catalyst, only 1-chlorine-3-alkoxycarbonylmethyltio-2-propa-nols are obtained the reaction of mercaptoacetic acid esters with epichlorohydrin. As a result of the interaction of mercapto-acetic acid esters with thioepichlorohydrin in the presence of equimolar amounts of sodium hydroxide, 2,3-epitiopropylalkoxycarbonylmethyl sulfides are formed as the only products of the reaction