2015
DOI: 10.3109/09638288.2014.996299
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Investigation of the effect of conservative interventions in thumb carpometacarpal osteoarthritis: systematic review and meta-analysis

Abstract: Manual therapy and exercise are an effective means of improving pain and function at short-term follow-up by patients with thumb CMC OA. Magneto therapy, manual therapy, manual therapy and exercise and Orthoses (splints) were found to have clinically significant results. Very few of the included studies showed a clinically significant effect size in favor of treatment.

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Cited by 99 publications
(94 citation statements)
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“…Our study demonstrated a large treatment effect with a CI that did not cross 0. The effect size of orthoses (splints) on pain reduction was small and not significant (g = 0.46) with a range from -1.08-0.16 at a short-term followup, while it was very large but not significant (g = 1.65) with a range from -4.04-0.74 at a longterm followup 5 . Manual therapy was effective in the reduction of pain at the short-term followup (effect size of g = -1.86), with a range of -3.700 --0.025.…”
Section: To the Editormentioning
confidence: 98%
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“…Our study demonstrated a large treatment effect with a CI that did not cross 0. The effect size of orthoses (splints) on pain reduction was small and not significant (g = 0.46) with a range from -1.08-0.16 at a short-term followup, while it was very large but not significant (g = 1.65) with a range from -4.04-0.74 at a longterm followup 5 . Manual therapy was effective in the reduction of pain at the short-term followup (effect size of g = -1.86), with a range of -3.700 --0.025.…”
Section: To the Editormentioning
confidence: 98%
“…There is moderate quality evidence that manual therapy and therapeutic exercise improves pain in patients with thumb CMC OA at both short-and intermediate-term followup 5 . There is some evidence that both steroid and hyaluronate intraarticular injections can reduce pain 6 , and low to moderate quality evidence that magnetic therapy improves pain and function at short-term followup (effect size for pain -1.39, 95% CI -2.00 --0.78) 5 . The effect of manual therapy and therapeutic exercise had a large effect size of -116.67, with a 95% CI of -137.55 --95.78 for the reduction of pain 13 .…”
Section: To the Editormentioning
confidence: 99%
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