Investigation of the effectiveness of Syzygium aromaticum, Lavandula angustifolia and Geranium robertianum essential oils in the treatment of acute external otitis: A comparative trial with ciprofloxacin

Panahi, Yunes; Akhavan, Asghar; Sahebkar, Amirhossein; Hosseini, Seied Mohammad; Taghizadeh, Mohsen; Akbari, Hossein; Sharif, Mohammad Reza; Imani, Saber

doi:10.1016/j.jmii.2012.10.002

Cited by 27 publications

(21 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Experimentally induced otitis media in rats could be cured in a high proportion of animals by the use of basil oil [63]. Treatment of human otitis patients with ear drops containing clove, lavender, and herb-Robert showed a healing effect comparable to that of ciprofloxacin ear drops (0.3%) [64].…”

Section: Discussionmentioning

confidence: 99%

Antifungal in vitro Activity of Essential Oils against Clinical Isolates of Malassezia pachydermatis from Canine Ears: A Report from a Practice Laboratory

et al. 2019

View full text Add to dashboard Cite

Background: The yeast Malassezia pachydermatis is a commensal but also the most isolated pathogenic yeast in canine otitis externa. Essential oils (EOs) exhibit antimicrobial activity and thus could be an alternative for treatment of otitis. Objective: The aim of this study was to analyse the in vitro efficacy of EOs against M. pachydermatis isolates from canine ears. Materials and Methods: Twenty-two EOs were tested for their in vitro activity against 15 M. pachydermatis isolates by agar disc diffusion. In addition, diluted EOs were tested and volatile antifungal activity was analysed by vapour assay. Results: Most EOs showed in vitro efficacy against M. pachydermatis. A different susceptibility pattern of tested isolates was found. Overall, the most potential EO was lemon grass. Also, cinnamon leaf, clove, manuka, Indian melissa, oregano, palmarosa, and winter savory oil exhibited a strong antifungal activity. Volatile activity was proven by the inhibiting effect in vapour assay. Conclusion: EOs show in vitro activity against M. pachydermatis. This study gives scientific background for the use of EOs in veterinary medicine. Diverse susceptibility patterns of different M. pachydermatis strains emphasise the helpfulness of an aromatogram as one lead for the best choice of an EO for therapy. Antimykotische In-vitro-Wirksamkeit ätherischerÖle gegen Malassezia pachydermatis isoliert aus Hundeohren: Ein Bericht aus dem Routinelabor Schlüsselwörter Ätherische Öle · Malassezia pachydermatis · Otitis externa · Veterinärmedizin Zusammenfassung Einleitung: Der Hefepilz Malassezia pachydermatis gilt als Kommensale, ist aber gleichzeitig auch der am häufigsten isolierte Hefepilz bei caniner Otitis externa. Ätherische Öle könnten aufgrund ihrer antimikrobiellen Eigenschaften als alternative Therapie der Otitis verwendet werden. Zielsetzung: Ziel dieser Studie war die Untersuchung der antifungalen In-vitro-Wirksamkeit ätherischer Öle gegen M. pachydermatis-Isolate aus Hundeohren. Material und Methoden: Die In-vitro-Aktivität von 22 ätherischen Ölen wurde mittels Agar-Plättchen-Diffusionstest gegen 15 M. pachydermatis-Isolate untersucht. Zusätzlich wurden Verdünnungen der ätherischen Öle getestet und die volatile Wirkung mittels "vapour assay" analysiert. Ergebnisse: Die meisten ätherischen Öle zeigten in vitro eine Wirksamkeit gegen M. pachydermatis. Es konnte eine unterschiedliche Empfindlichkeit einzelner M. pachydermatis-Isolate gefunden werden. Lemongrasöl erwies sich als das po-tenteste ätherische Öl. Ebenfalls zeigten Zimtblätter-, Nelken-, Manuka-, indisches Melissen-, Oregano-, Palmarosa-und Bergbohnenkrautöl eine starke antifungale Wirksamkeit. Die volatile Wirkung konnte mittels "vapour assay" gezeigt werden. Schlussfolgerung: In vitro zeigen ätherische Öle eine Wirksamkeit gegen den Hefepilz M. pachydermatis. Diese Studie bietet eine wissenschaftliche Basis zur Anwendung ätherischer Öle in der Veterinärmedizin. Die unterschiedliche Empfindlichkeit der verschiedenen M. pachydermatis-Isolate gegenüber einzelner äther...

show abstract

Section: Discussionmentioning

confidence: 99%

Antifungal in vitro Activity of Essential Oils against Clinical Isolates of Malassezia pachydermatis from Canine Ears: A Report from a Practice Laboratory

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Thyme and its oil have also a long reputation in the Iranian folk [6][7][8] . Essential oils are regarded as important herbal products with biological and pharmacological activities [13][14][15][16][17][18][19][20] . Composition of an essential oil is influenced by a variety of factors related to geographical, climatic, cultivation and seasonal variations.…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition of the Essential Oil ofThymus vulgarisL. Grown in Iran

Abedini

Sahebkar

Hassanzadeh-Khayyat

2014

Journal of Essential Oil Bearing Plants

Self Cite

View full text Add to dashboard Cite

Thyme (Thymus vulgaris L.), family Labiateae, is fairly grown wildly throughout Iran. The essential oil of the aerial parts of T. vulgaris, cultivated in the Khorasan province, North East of Iran, was prepared. The chemical composition of the oil was identified using GC-MS. Twenty-one compounds were identified. The major components of the oil were carvacrol (57.3 %), linalool (11.8 %) and thymol (10.67 %). The amounts of the two main components, carvacrol and thymol, were compared with the results reported from other countries.

show abstract

“…However, the rate of pain improvement was different between the two groups. The number of positive cultures was also reduced by ciprofloxacin and Lamigex treatment by the end of the trial . It is necessary to highlight that undiluted EOs should not be dripped into the ears, but diluted EOs may be placed on a cotton wad for partial insertion…”

Section: Human Trialsmentioning

confidence: 97%

“…Panahi et al . investigated the effectiveness of a herbal product (Lamigex) containing the EO of Syzygium aromaticum , Lavandula angustifolia and Geranium robertianum in the treatment of acute external otitis (AEO) and compared its effects to those of ciprofloxacin.…”

Section: Human Trialsmentioning

confidence: 99%

Essential oils in the treatment of respiratory tract diseases highlighting their role in bacterial infections and their anti‐inflammatory action: a review

Horváth

Ács

2015

Flavour & Fragrance J

106

View full text Add to dashboard Cite

The appearance of multidrug resistant bacteria and growing antibiotic resistance is leading to a continuous need for discovering new drugs and alternative treatments against infections. The investigation of the antibacterial effect of essential oils (EOs), which are commonly used nowadays in cosmetics, health care, traditional medicine and food industry, could be one of the promising solutions for this worldwide problem. EOs have a complex mode of action due to their multiple composition. Respiratory tract diseases (RTDs) associated with bacterial infection and inflammation affect a large number of people from every age group worldwide. Because of volatility, EOs can easily reach the upper and lower parts of the respiratory tract via inhalation. Moreover, due to their antimicrobial and anti-inflammatory potency, they offer an effective treatment in respiratory tract infections (RTIs). The purpose of this review is to describe the most frequently developing infections of the upper and lower respiratory tract and to show methods used for the determination of the antibacterial activity of EOs by gaseous contact. The mode of action of EOs on bacterial cells and their anti-inflammatory action are also discussed. Results coming from recently performed in vivo animal studies as well as human trials are also reported. Patents deal with the role of EOs and their volatile constituents in the treatment of RTIs are also introduced. On the whole, this review aimed at showing EOs as potential antimicrobials and as anti-inflammatory agents to alleviate symptoms and signs of RTDs including RTIs.

show abstract

Investigation of the effectiveness of Syzygium aromaticum, Lavandula angustifolia and Geranium robertianum essential oils in the treatment of acute external otitis: A comparative trial with ciprofloxacin

Abstract: The herbal combination drop that was investigated in the present study exhibited good efficacy in reducing the burden of infection as well as AEO symptoms.

Cited by 27 publications

References 23 publications

Antifungal in vitro Activity of Essential Oils against Clinical Isolates of <b><i>Malassezia pachydermatis</i></b> from Canine Ears: A Report from a Practice Laboratory

Antifungal in vitro Activity of Essential Oils against Clinical Isolates of <b><i>Malassezia pachydermatis</i></b> from Canine Ears: A Report from a Practice Laboratory

Chemical Composition of the Essential Oil ofThymus vulgarisL. Grown in Iran

Essential oils in the treatment of respiratory tract diseases highlighting their role in bacterial infections and their anti‐inflammatory action: a review

Contact Info

Product

Resources

About