Investigation of the Effectiveness of Microvascular Doppler Ultrasound and Q-Pack in the Discrimination of Malign Thyroid Nodules From Benign

Abstract

In this prospective study, the diagnostic performance of MicroV Doppler ultrasonography (US) and Q-pack application in distinguishing malignant thyroid nodules from benign nodules will be examined. Given the emerging irregular vascular structures in malignant nodules, it is thought that MicroV Doppler US and Q-pack application can help in diagnosis. One hundred sixteen nodules that were suggested a biopsy by a clinician were examined with B-mode US, color, X-flow, and MicroV Doppler US, respectively. In addition, during MicroV Doppler US examination, thyroid nodule and its adjacent thyroid parenchyma were evaluated with Q-pack application. After US examinations, biopsy was performed on the nodules and histopathological results were obtained. Eighty-nine nodules were histopathologically proven as benign, and the rest of them were malignant. In Doppler types, the thyroid findings in score 1, 2, and 3 nodule blood supply type were benign, whereas the thyroid findings in the score 4 have a possibility of malignancy between 63% and 66.7%. It was found that MicroV Doppler was significantly superior to X-flow and color Doppler ( P = 0.037 and P = 0.042, respectively). Nodule/parenchyma Q-pack mean values were statistically significantly higher in malignant findings compared with benign findings ( P < 0.001). Nodule/parenchyma Q-pack peak values were also statistically significantly higher in malignant findings compared with benign findings ( P < 0.001). As a result, although Q-pack application enables us to obtain quantitative values about vascularity, due to its ability to demonstrate slow blood flow, microvascular vessel structure, and distribution, MicroV Doppler US has promises to detect malignant thyroid nodules.

Diagnostic efficacy of ultrasonography, Doppler ultrasonography and elastography in the evaluation of suspected malignant lymph nodes

“…In studies performed according to vascular distribution patterns on Doppler US, hilar blood supply was observed in normal and reactive lymph nodes, while peripheral and mixed (hilar + peripheral) blood supply was seen in malignant lymph nodes ( 11 , 12 , 13 , 14 ) . However, the study by Ying et al .…”

“…In studies performed according to vascular distribution patterns on Doppler US, hilar blood supply was observed in normal and reactive lymph nodes, while peripheral and mixed (hilar + peripheral) blood supply was seen in malignant lymph nodes (11)(12)(13)(14) . However, the study by Ying et al found that while peripheral blood supply was observed in metastatic lymph nodes, hilar vascular structures were also preserved in lymphomatous lymph nodes, and there was a tendency for both hilar and peripheral blood supply (15) .…”

A radiological and clinical overview of the effects of COVID-19 on the male reproductive system: micro V Doppler, spermiogram and international erectile function form survey results

“…For this reason, they also delete the slow flow which considered as an artifact. Doppler methods have been developed by different companies, which use the recently developed high frame rate and can see microvascular structures with its unique algorithm rather than large-medium diameter vascular structures (Esoate: Micro V Doppler and Toshiba: Superb microvascular imaging) (5,6). There are publications reporting that microvascular imaging techniques are extremely successful in superficial organs such as testis and breast in examinations performed with a lineer probe (13).…”

“…In grade 3 vascularity, more than two vascular structures are seen. Multiple irregularly shaped and curved microvascular structures in the center and periphery of the parenchyma is defined as grade 4 (5,6).…”